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Table 2.

Response of adult northern female elephant seals to 150 g exogenous glucose in early and late lactation and post-molt

Early lactationLate lactationPost-molt
Insulin levels 10 min post GTT (pg ml–1175.0±20.4a 36.6±11.9b 132.3±5.5a 
Insulin response (% increase in 10 min) 129.0±24.4a –4.8±21.6b 61.6±11.6c 
Mean insulin secreted (pg ml–10.045±0.012a,* 0.009±0.006b 0.026±0.005a,* 
Insulin sensitivity index (Is3.4×10–4±9.4×10–5a 6.1×10–5±4.4×10–5b 2.5×10–4±5.4×10–5a 
Glucose tolerance index (K; % min–10.27±0.02 0.19±0.05 0.27±0.03 
Mean glucose present (mg dl–1123.0±6.0 140.7±8.1 117.4±15.6 
Early lactationLate lactationPost-molt
Insulin levels 10 min post GTT (pg ml–1175.0±20.4a 36.6±11.9b 132.3±5.5a 
Insulin response (% increase in 10 min) 129.0±24.4a –4.8±21.6b 61.6±11.6c 
Mean insulin secreted (pg ml–10.045±0.012a,* 0.009±0.006b 0.026±0.005a,* 
Insulin sensitivity index (Is3.4×10–4±9.4×10–5a 6.1×10–5±4.4×10–5b 2.5×10–4±5.4×10–5a 
Glucose tolerance index (K; % min–10.27±0.02 0.19±0.05 0.27±0.03 
Mean glucose present (mg dl–1123.0±6.0 140.7±8.1 117.4±15.6 

Early and late samples are from 5 and 22 days postpartum,respectively

K, glucose tolerance index (see Materials and methods for calculation). Mean glucose present was calculated as the area under the curve(AUC)glucose divided by the total duration (in min) of the sampling period. Mean hormone secreted was calculated as AUChormone divided by the total duration (in min) of the sampling period. See Materials and methods for calculation of Is. Different superscript letters within rows indicate a significantly difference at P<0.05;asterisks within rows indicate a significant response to the glucose tolerance test (GTT; RM ANOVA P<0.05)

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