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Table 1.

List of PKs upregulated during mesendoderm differentiation

RankValue*Affimetrix IDGroupFamilyGene (source)
1 0.140874 104066_at Other Other - unique Expressed sequence AW548124 (MGI:2147077) 
2 0.184352 98452_at TK VEGFR FMS-like tyrosine kinase 1 (MGI:95558) 
3 0.189161 163489_at TKL RIPK receptor-interacting serine-threonine kinase 4 (MGI:1919638) 
4 0.191523 111233_at AGC PKC protein kinase C, eta (MGI:97600) 
5 0.196463 113139_at CAMK TRBL tribbles homolog 2 (Drosophila) (MGI:2145021) 
6 0.227337 112692_at STE STE20 RIKEN cDNA 2610018G03 gene (MGI:1917665) 
7 0.244947 114748_at CAMK DAPK death associated protein kinase 1 (MGI:1916885) 
8 0.311274 114925_at STE STE20 TRAF2 and NCK interacting kinase (MGI:1916264) 
9 0.325234 115909_at CAMK CAMKL SNF1-like kinase 2 (MGI:2445031) 
10 0.328924 112442_at TK ACK tyrosine kinase, non-receptor, 1 (MGI:1930958) 
11 0.342771 106573_at CAMK CAMKL SNF related kinase (MGI:108104) 
12 0.353542 117151_at TK MET met proto-oncogene (MGI:96969) 
13 0.356705 112983_at TK ROR receptor tyrosine kinase-like orphan receptor 1 (MGI:1347520) 
14 0.36157 107580_g_at AGC DMPK Cdc42 binding protein kinase beta (MGI:2136459) 
15 0.393467 163536_at CK1 CK1 casein kinase 1, gamma 3 (MGI:1917675) 
16 0.395264 107465_at CAMK CAMK1 calcium/calmodulin-dependent protein kinase ID (MGI:2442190) 
17 0.413686 110852_at Atypical PIKK transformation/transcription domain-associated protein (MGI:2153272) 
18 0.414039 92427_at TKL STKR transforming growth factor, beta receptor I (MGI:98728) 
19 0.425736 115874_at STE STE20 p21 (CDKN1A)-activated kinase 1 (MGI:1339975) 
20 0.429529 141026_at Other NKF3 Adult male bone cDNA, RIKEN full-length enriched library, clone: 9830148H23 product: hypothetical protein kinase-like (PK-like) structure containing protein, full insert sequence (DNA segment, Chr 8, ERATO Doi 82, expressed)(Uniprot/SPTREMBL;Acc:Q8CB68) 
21 0.433359 103592_at STE STE7 mitogen activated protein kinase kinase 5 (MGI:1346345) 
22 0.436237 117265_at Other SCY1 SCY1-like 1 (S. cerevisiae) (MGI:1931787) 
23 0.438849 105742_at AGC AKT thymoma viral proto-oncogene 3 (MGI:1345147) 
24 0.44402 132114_f_at Other WNK WNK lysine deficient protein kinase 4 (MGI:1917097) 
25 0.449448 167725_f_at CMGC CDK PFTAIRE protein kinase 1 (MGI:894318) 
26 0.454032 168469_f_at Other NKF2 PTEN induced putative kinase 1 (MGI:1916193) 
27 0.456906 111539_at Other SCY1 SCY1-like 2 (S. cerevisiae) (MGI:1289172) 
28 0.458283 105428_at CAMK MAPKAPK mitogen-activated protein kinase-activated protein kinase 3 (MGI:2143163) 
29 0.464858 108785_at STE STE11 mitogen activated protein kinase kinase kinase 7 (MGI:1346877) 
30 0.468153 93723_at TK ROR receptor tyrosine kinase-like orphan receptor 2 (MGI:1347521) 
31 0.47274 99388_at TK SRC Rous sarcoma oncogene (MGI:98397) 
32 0.475296 112462_at CMGC DYRK homeodomain interacting protein kinase 3 (MGI:1314882) 
33 0.49409 99000_at CMGC MAPK mitogen activated protein kinase 7 (MGI:1346347) 
34 0.51967 111507_at STE STE7 mitogen activated protein kinase kinase 4 (MGI:1346869) 
35 0.521478 138075_at CMGC MAPK mitogen activated protein kinase 9 (MGI:1346862) 
36 0.572143 162716_at Other IKK inhibitor of kappaB kinase beta (MGI:1338071) 
RankValue*Affimetrix IDGroupFamilyGene (source)
1 0.140874 104066_at Other Other - unique Expressed sequence AW548124 (MGI:2147077) 
2 0.184352 98452_at TK VEGFR FMS-like tyrosine kinase 1 (MGI:95558) 
3 0.189161 163489_at TKL RIPK receptor-interacting serine-threonine kinase 4 (MGI:1919638) 
4 0.191523 111233_at AGC PKC protein kinase C, eta (MGI:97600) 
5 0.196463 113139_at CAMK TRBL tribbles homolog 2 (Drosophila) (MGI:2145021) 
6 0.227337 112692_at STE STE20 RIKEN cDNA 2610018G03 gene (MGI:1917665) 
7 0.244947 114748_at CAMK DAPK death associated protein kinase 1 (MGI:1916885) 
8 0.311274 114925_at STE STE20 TRAF2 and NCK interacting kinase (MGI:1916264) 
9 0.325234 115909_at CAMK CAMKL SNF1-like kinase 2 (MGI:2445031) 
10 0.328924 112442_at TK ACK tyrosine kinase, non-receptor, 1 (MGI:1930958) 
11 0.342771 106573_at CAMK CAMKL SNF related kinase (MGI:108104) 
12 0.353542 117151_at TK MET met proto-oncogene (MGI:96969) 
13 0.356705 112983_at TK ROR receptor tyrosine kinase-like orphan receptor 1 (MGI:1347520) 
14 0.36157 107580_g_at AGC DMPK Cdc42 binding protein kinase beta (MGI:2136459) 
15 0.393467 163536_at CK1 CK1 casein kinase 1, gamma 3 (MGI:1917675) 
16 0.395264 107465_at CAMK CAMK1 calcium/calmodulin-dependent protein kinase ID (MGI:2442190) 
17 0.413686 110852_at Atypical PIKK transformation/transcription domain-associated protein (MGI:2153272) 
18 0.414039 92427_at TKL STKR transforming growth factor, beta receptor I (MGI:98728) 
19 0.425736 115874_at STE STE20 p21 (CDKN1A)-activated kinase 1 (MGI:1339975) 
20 0.429529 141026_at Other NKF3 Adult male bone cDNA, RIKEN full-length enriched library, clone: 9830148H23 product: hypothetical protein kinase-like (PK-like) structure containing protein, full insert sequence (DNA segment, Chr 8, ERATO Doi 82, expressed)(Uniprot/SPTREMBL;Acc:Q8CB68) 
21 0.433359 103592_at STE STE7 mitogen activated protein kinase kinase 5 (MGI:1346345) 
22 0.436237 117265_at Other SCY1 SCY1-like 1 (S. cerevisiae) (MGI:1931787) 
23 0.438849 105742_at AGC AKT thymoma viral proto-oncogene 3 (MGI:1345147) 
24 0.44402 132114_f_at Other WNK WNK lysine deficient protein kinase 4 (MGI:1917097) 
25 0.449448 167725_f_at CMGC CDK PFTAIRE protein kinase 1 (MGI:894318) 
26 0.454032 168469_f_at Other NKF2 PTEN induced putative kinase 1 (MGI:1916193) 
27 0.456906 111539_at Other SCY1 SCY1-like 2 (S. cerevisiae) (MGI:1289172) 
28 0.458283 105428_at CAMK MAPKAPK mitogen-activated protein kinase-activated protein kinase 3 (MGI:2143163) 
29 0.464858 108785_at STE STE11 mitogen activated protein kinase kinase kinase 7 (MGI:1346877) 
30 0.468153 93723_at TK ROR receptor tyrosine kinase-like orphan receptor 2 (MGI:1347521) 
31 0.47274 99388_at TK SRC Rous sarcoma oncogene (MGI:98397) 
32 0.475296 112462_at CMGC DYRK homeodomain interacting protein kinase 3 (MGI:1314882) 
33 0.49409 99000_at CMGC MAPK mitogen activated protein kinase 7 (MGI:1346347) 
34 0.51967 111507_at STE STE7 mitogen activated protein kinase kinase 4 (MGI:1346869) 
35 0.521478 138075_at CMGC MAPK mitogen activated protein kinase 9 (MGI:1346862) 
36 0.572143 162716_at Other IKK inhibitor of kappaB kinase beta (MGI:1338071) 

PKs expressed in ES cell-derived mesendoderm cells are listed (PKs that are expressed in ES cells are excluded from this list).

*

Value indicates a distance measurement based on Euclidean distances to a specified profile.

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