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Table 1.

Effects of misexpression of TSK and VG1 in the area pellucida

MoleculeSample/total%
TSKA 0/8 
TSKB 0/10 
VG1 6/28 21 
VG1 + WNT1 9/14 64 
TSKA + VG1 18/30 60 
TSKB + VG1 23/46 50 
TSKA + VG1 + WNT1 26/30 87 
TSKB + VG1 + WNT1 25/29 86 
MoleculeSample/total%
TSKA 0/8 
TSKB 0/10 
VG1 6/28 21 
VG1 + WNT1 9/14 64 
TSKA + VG1 18/30 60 
TSKB + VG1 23/46 50 
TSKA + VG1 + WNT1 26/30 87 
TSKB + VG1 + WNT1 25/29 86 

A pellet of cells expressing above molecule was grafted into the area pellucida of pre-streak stage XII embryos; 24 hours later, the ectopic induction of brachyury, a marker for primitive streak, was examined by in situ hybridization.

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