Number and percentage of embryos showing defects in the distribution of vagus motor neurons
. | Phenotype (genotype) . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
mRNA . | Mutant (–/–) . | Weak(–/–)* . | Wild (–/–) . | Wild (+/+, +/–) . | Total . | ||||
No injection | 17 | 0 | 0 | 54 | 71 | ||||
L-gmds (wild type) | |||||||||
80 μg/ml | 0 (0%) | 3 (13%) | 21 (88%) | 82 | 107 | ||||
40 μg/ml | 5 (19%) | 8 (30%) | 14 (52%) | 78 | 105 | ||||
S-gmds (wild type) | |||||||||
80 μg/ml | 0 (0%) | 8 (27%) | 22 (73%) | 82 | 112 | ||||
40 μg/ml | 9 (31%) | 9 (31%) | 11 (38%) | 83 | 112 | ||||
L-gmds (twdrw685) | |||||||||
80 μg/ml | 37 (100%) | 0 | 0 | 95 | 132 | ||||
40 μg/ml | 28 (100%) | 0 | 0 | 80 | 108 | ||||
S-gmds (twdrw685) | |||||||||
80 μg/ml | 37 (100%) | 0 | 0 | 111 | 148 | ||||
40 μg/ml | 28 (100%) | 0 | 0 | 88 | 116 |
. | Phenotype (genotype) . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
mRNA . | Mutant (–/–) . | Weak(–/–)* . | Wild (–/–) . | Wild (+/+, +/–) . | Total . | ||||
No injection | 17 | 0 | 0 | 54 | 71 | ||||
L-gmds (wild type) | |||||||||
80 μg/ml | 0 (0%) | 3 (13%) | 21 (88%) | 82 | 107 | ||||
40 μg/ml | 5 (19%) | 8 (30%) | 14 (52%) | 78 | 105 | ||||
S-gmds (wild type) | |||||||||
80 μg/ml | 0 (0%) | 8 (27%) | 22 (73%) | 82 | 112 | ||||
40 μg/ml | 9 (31%) | 9 (31%) | 11 (38%) | 83 | 112 | ||||
L-gmds (twdrw685) | |||||||||
80 μg/ml | 37 (100%) | 0 | 0 | 95 | 132 | ||||
40 μg/ml | 28 (100%) | 0 | 0 | 80 | 108 | ||||
S-gmds (twdrw685) | |||||||||
80 μg/ml | 37 (100%) | 0 | 0 | 111 | 148 | ||||
40 μg/ml | 28 (100%) | 0 | 0 | 88 | 116 |
Number (%) of the rescued twdrw685 embryos
Distribution of vagus motor neurons is slightly abnormal compared with that of the wild type