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Table 1.

Effect of phospholipase A2 neurotoxin intoxication on the twitch of mouse phrenic-nerve hemidiaphragm preparations

Concentration Maximum facilitation (% ctr)* Duration of facilitation (minutes) Paralysis time (minutes)
β-BTx   3 μg ml-1  140.7±7   17±2.6   148±6.1  
Taipoxin   1 μg ml-1  138.8±9   19.5±1.3   56.4±6.7  
Notexin   1 μg ml-1  ND   ND   42±2.8  
Textilotoxin   1 μg ml-1  127±6.2   24.3±5.1   76.7±5.7  
Concentration Maximum facilitation (% ctr)* Duration of facilitation (minutes) Paralysis time (minutes)
β-BTx   3 μg ml-1  140.7±7   17±2.6   148±6.1  
Taipoxin   1 μg ml-1  138.8±9   19.5±1.3   56.4±6.7  
Notexin   1 μg ml-1  ND   ND   42±2.8  
Textilotoxin   1 μg ml-1  127±6.2   24.3±5.1   76.7±5.7  

Data are means of three different experiments; ND, not determined.

*

Percentage with respect to the control twitch (i.e. before adding tonin)

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