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Table 1.

Different types of intermediate filaments and their movements

Cytoplasmic intermediate filament type Protein studied Cell type Structural form observed Published results n= Time moving (%) Time pausing (%) Antero movements (%) Retro movements (%) Average antero motility (mm/sec) Range antero (μm/sec) Average retro motility (μm/sec) Range retro (μm/sec)
Type I   Keratin 13   AK13-1   Particles (dots)  Windoffer and Leube, 1999       Mostly Retro    0.002-0.008    0.002-0.008  
  Keratin 18   PtK2   Squiggles  Yoon et al., 2001   37   18*  82   16   84   0.004±0.03   0.002-0.01   0.004±0.03   0.002-0.01  
Type II   Keratin 5   NEB-1   Particles  Liovic et al., 2003   16        >0.1    >0.1  
  Keratin 8   PtK2   Filaments  Yoon et al., 2001   14       0.001±3.33E-05    0.001±3.33E-05   
Type III   Vimentin   BHK-21   Particles  Helfand et al., 2003   53   45   55   66   34   0.39±0.24   0.08-1.65   0.43±0.26   0.08-1.40  
    Squiggles  Yoon et al., 1998   32     97   3   0.06±0.03   0.02-0.19   0.06±0.03   0.02-0.19  
    Filaments  Yoon et al., 1998   23       0.004±0.002    0.004±0.002   
  Vimentin   PtK2   Squiggles  Yoon et al., 2001   32     70   30   0.06±0.04   0.006-0.15   0.06±0.04   0.006-0.15  
    Filaments  Yoon et al., 2001   29       0.15±0.11    0.15±0.11   
  Vimentin   3T3   Squiggles  Martys et al., 1999        0.25    0.25   
  Peripherin   PC12   Particles  Helfand et al., 2003   77   75   25   65   35   0.33±0.24   0.08-1.45   0.30±0.20   0.08-1.54  
    Squiggles  Helfand et al., 2003   50   70   30   62   38   0.31±0.29   0.08-1.21   0.30±0.28   0.08-1.00  
Type IV   NF-M   Rat sympathetic neurons   Short filaments  Wang et al., 2000   69   27   73   83   17   0.38   0.02-1.21   0.49   0.15-1.82  
  NF-M   Rat sympathetic neurons   Short filaments   Wang et al., 2001   69   33   67   69   31   0.56   0.15-1.26   0.62   0.17-1.35  
  NF-M   Rat sympathetic neurons   Particles   Wang et al., 2001   17   56   44   22   88   0.08   0.06-0.10   0.32   0.13-0.60  
  NF-M   NB2a/d1   Particles  Yabe et al., 1999      >80%   <20%   0.025±0.005     
  NF-H   Rat sympathetic neurons   Short filaments  Roy et al., 2000   73   20   80   71   29   0.67   0.14-1.7   0.57   0.11-1.4  
  NF-L, NF-M, NF-H   Purified bovine spinal cordrrrr   Short filaments  Shah et al., 2000        0.27   ∼0.1-0.85   0.29   ∼0.1-1  
  NF-L, NF-M, NF-H   Axoplasm from Loligo pealei  Particles  Prahlad et al., 2000   10        0.5-1.0    0.5-1.0  
Cytoplasmic intermediate filament type Protein studied Cell type Structural form observed Published results n= Time moving (%) Time pausing (%) Antero movements (%) Retro movements (%) Average antero motility (mm/sec) Range antero (μm/sec) Average retro motility (μm/sec) Range retro (μm/sec)
Type I   Keratin 13   AK13-1   Particles (dots)  Windoffer and Leube, 1999       Mostly Retro    0.002-0.008    0.002-0.008  
  Keratin 18   PtK2   Squiggles  Yoon et al., 2001   37   18*  82   16   84   0.004±0.03   0.002-0.01   0.004±0.03   0.002-0.01  
Type II   Keratin 5   NEB-1   Particles  Liovic et al., 2003   16        >0.1    >0.1  
  Keratin 8   PtK2   Filaments  Yoon et al., 2001   14       0.001±3.33E-05    0.001±3.33E-05   
Type III   Vimentin   BHK-21   Particles  Helfand et al., 2003   53   45   55   66   34   0.39±0.24   0.08-1.65   0.43±0.26   0.08-1.40  
    Squiggles  Yoon et al., 1998   32     97   3   0.06±0.03   0.02-0.19   0.06±0.03   0.02-0.19  
    Filaments  Yoon et al., 1998   23       0.004±0.002    0.004±0.002   
  Vimentin   PtK2   Squiggles  Yoon et al., 2001   32     70   30   0.06±0.04   0.006-0.15   0.06±0.04   0.006-0.15  
    Filaments  Yoon et al., 2001   29       0.15±0.11    0.15±0.11   
  Vimentin   3T3   Squiggles  Martys et al., 1999        0.25    0.25   
  Peripherin   PC12   Particles  Helfand et al., 2003   77   75   25   65   35   0.33±0.24   0.08-1.45   0.30±0.20   0.08-1.54  
    Squiggles  Helfand et al., 2003   50   70   30   62   38   0.31±0.29   0.08-1.21   0.30±0.28   0.08-1.00  
Type IV   NF-M   Rat sympathetic neurons   Short filaments  Wang et al., 2000   69   27   73   83   17   0.38   0.02-1.21   0.49   0.15-1.82  
  NF-M   Rat sympathetic neurons   Short filaments   Wang et al., 2001   69   33   67   69   31   0.56   0.15-1.26   0.62   0.17-1.35  
  NF-M   Rat sympathetic neurons   Particles   Wang et al., 2001   17   56   44   22   88   0.08   0.06-0.10   0.32   0.13-0.60  
  NF-M   NB2a/d1   Particles  Yabe et al., 1999      >80%   <20%   0.025±0.005     
  NF-H   Rat sympathetic neurons   Short filaments  Roy et al., 2000   73   20   80   71   29   0.67   0.14-1.7   0.57   0.11-1.4  
  NF-L, NF-M, NF-H   Purified bovine spinal cordrrrr   Short filaments  Shah et al., 2000        0.27   ∼0.1-0.85   0.29   ∼0.1-1  
  NF-L, NF-M, NF-H   Axoplasm from Loligo pealei  Particles  Prahlad et al., 2000   10        0.5-1.0    0.5-1.0  
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