Skip to Main Content
Table 1.

Function and expression pattern of aquaporins

AQP Permeability Tissue expression
AQP0   ?   Eye lens fiber cells  
AQP1   Water   Kidney tubules, endothelia, erythrocytes, choroid plexus, ciliary epithelium, intestinal lacteals, corneal endothelium  
AQP2   Water   Kidney collecting duct  
AQP3   Water, glycerol   Kidney collecting duct, epidermis, airway epithelium, conjunctiva, large airways, urinary bladder  
AQP4   Water   Astroglia in brain and spinal cord, kidney collecting duct, glandular epithelia, airways, skeletal muscle, stomach, retina  
AQP5   Water   Glandular epithelia, corneal epithelium, alveolar epithelium, gastrointestinal tract  
AQP6   Chloride?   Kidney collecting duct intercalated cells  
AQP7   Water, glycerol   Adipose tissue, testis, kidney proximal tubule  
AQP8   Water   Liver, pancreas, intestine, salivary gland, testis, heart  
AQP9   Water, small solutes   Liver, white blood cells, testis, brain  
AQP10   Water, glycerol   Small intestine  
AQP11   ?   Kidney, liver  
AQP12   ?   Pancreatic acinar cells  
AQP Permeability Tissue expression
AQP0   ?   Eye lens fiber cells  
AQP1   Water   Kidney tubules, endothelia, erythrocytes, choroid plexus, ciliary epithelium, intestinal lacteals, corneal endothelium  
AQP2   Water   Kidney collecting duct  
AQP3   Water, glycerol   Kidney collecting duct, epidermis, airway epithelium, conjunctiva, large airways, urinary bladder  
AQP4   Water   Astroglia in brain and spinal cord, kidney collecting duct, glandular epithelia, airways, skeletal muscle, stomach, retina  
AQP5   Water   Glandular epithelia, corneal epithelium, alveolar epithelium, gastrointestinal tract  
AQP6   Chloride?   Kidney collecting duct intercalated cells  
AQP7   Water, glycerol   Adipose tissue, testis, kidney proximal tubule  
AQP8   Water   Liver, pancreas, intestine, salivary gland, testis, heart  
AQP9   Water, small solutes   Liver, white blood cells, testis, brain  
AQP10   Water, glycerol   Small intestine  
AQP11   ?   Kidney, liver  
AQP12   ?   Pancreatic acinar cells  
Close Modal

or Create an Account

Close Modal
Close Modal