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Table 1.

Tissue wet-weight, DA and DOPAC content in the forebrain of Ngn2 mutant mice

Wild type (n=6)Ngn2-/- (n=4)
Weight (mg) 305±4 231±5(75%)* 
DA total (pmol) 1207±33 458±48(38%)* 
DOPAC total (pmol) 185±13 88±8(48%)* 
DOPAC/DA ratio 0.15 0.19 
DA concentration (pmol/mg) 3.96±0.11 1.99±0.14(50%)* 
DOPAC concentration (pmol/mg) 0.61±0.03 0.38±0.02(62%)* 
Wild type (n=6)Ngn2-/- (n=4)
Weight (mg) 305±4 231±5(75%)* 
DA total (pmol) 1207±33 458±48(38%)* 
DOPAC total (pmol) 185±13 88±8(48%)* 
DOPAC/DA ratio 0.15 0.19 
DA concentration (pmol/mg) 3.96±0.11 1.99±0.14(50%)* 
DOPAC concentration (pmol/mg) 0.61±0.03 0.38±0.02(62%)* 

The percentage of wild-type value is shown in parentheses.

*

Statistical significance at P<0.01 (unpaired Student's t-test)

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