Tissue wet-weight, DA and DOPAC content in the forebrain of Ngn2 mutant mice
| . | Wild type (n=6) . | Ngn2-/- (n=4) . |
|---|---|---|
| Weight (mg) | 305±4 | 231±5(75%)* |
| DA total (pmol) | 1207±33 | 458±48(38%)* |
| DOPAC total (pmol) | 185±13 | 88±8(48%)* |
| DOPAC/DA ratio | 0.15 | 0.19 |
| DA concentration (pmol/mg) | 3.96±0.11 | 1.99±0.14(50%)* |
| DOPAC concentration (pmol/mg) | 0.61±0.03 | 0.38±0.02(62%)* |
| . | Wild type (n=6) . | Ngn2-/- (n=4) . |
|---|---|---|
| Weight (mg) | 305±4 | 231±5(75%)* |
| DA total (pmol) | 1207±33 | 458±48(38%)* |
| DOPAC total (pmol) | 185±13 | 88±8(48%)* |
| DOPAC/DA ratio | 0.15 | 0.19 |
| DA concentration (pmol/mg) | 3.96±0.11 | 1.99±0.14(50%)* |
| DOPAC concentration (pmol/mg) | 0.61±0.03 | 0.38±0.02(62%)* |
The percentage of wild-type value is shown in parentheses.
Statistical significance at P<0.01 (unpaired Student's t-test)