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Table 1.

FGF signalling can induce bra but not Sax1 expression in HH stage 4 neural plate explants

Sax1*
bra*
Treatment4a4b4a4b
FGF4 (10 ng/ml) 4/4 0/4 4/4 0/4 
FGF4 (200 ng/ml) 1/3 0/3 2/2 2/2 
FGF8 (50 ng/ml) 3/5 0/5 4/4 1/4 
FGF8 (250 ng/ml) 2/3 1/6 2/3 1/4 
Sax1*
bra*
Treatment4a4b4a4b
FGF4 (10 ng/ml) 4/4 0/4 4/4 0/4 
FGF4 (200 ng/ml) 1/3 0/3 2/2 2/2 
FGF8 (50 ng/ml) 3/5 0/5 4/4 1/4 
FGF8 (250 ng/ml) 2/3 1/6 2/3 1/4 
*

Upregulation of expression observed in treated versus contralateral untreated explants.

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