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Table 1.

Panel of cellular and molecular markers used to screen for NMJ-capping-cell epitopes

Antibody/marker Cell type or antigen Antibody 2166 staining*
S100   Schwann cells   -  
GFAP   Reactive Schwann cells   -  
Nestin   Reactive Schwann cells   -  
M-Cadherin   Satellite cells   -  
NCAM   Satellite cells   -  
Desmin   Satellite cells   -  
Thy-1   Fibroblasts/neurons   -  
F4/80   Macrophages   -  
CD34   Stem cells   +  
rPH   Fibroblasts   +  
HM-24   GGFII-related molecules   +  
CTB   GM1 ganglioside   +  
Antibody/marker Cell type or antigen Antibody 2166 staining*
S100   Schwann cells   -  
GFAP   Reactive Schwann cells   -  
Nestin   Reactive Schwann cells   -  
M-Cadherin   Satellite cells   -  
NCAM   Satellite cells   -  
Desmin   Satellite cells   -  
Thy-1   Fibroblasts/neurons   -  
F4/80   Macrophages   -  
CD34   Stem cells   +  
rPH   Fibroblasts   +  
HM-24   GGFII-related molecules   +  
CTB   GM1 ganglioside   +  
*

Positive staining was obtained with CD34, rPH, HM-24 and CTB. Other markers of Schwann cells, macrophages, fibroblasts and other satellite cells did not stain NMJ-capping cells.

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