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Table 3.

Comparison of defects in gli mutant and MO-injected embryos

nk2.1b
ptc1 vent. CNSnk2.2 forebraindi.tel.fkd4 lateral floorplatemyoD adaxial cells
dtr/gli1-/- [UNK] [UNK][UNK] [UNK] wt [UNK][UNK] wt 
gli1 MO [UNK] [UNK][UNK] (likedtr[UNK] wt [UNK][UNK] wt 
yot/gli2-/- [UNK] [UNK][UNK] [UNK] wt [UNK][UNK] [UNK][UNK] 
gli2 MO wt/[UNK] wt wt/[UNK] [UNK] wt/[UNK] wt 
gli2 MO→yot-/- wt/[UNK] (rescue) wt (rescue) wt (rescue) [UNK] wt/[UNK] (rescue) [UNK] (rescue) 
gli2 MO→dtr-/- nd [UNK][UNK] (likedtr[UNK] (like dtr[UNK] nd [UNK] 
yot-/+;dtr-/+ [UNK] [UNK][UNK]nd nd [UNK] [UNK] 
nk2.1b
ptc1 vent. CNSnk2.2 forebraindi.tel.fkd4 lateral floorplatemyoD adaxial cells
dtr/gli1-/- [UNK] [UNK][UNK] [UNK] wt [UNK][UNK] wt 
gli1 MO [UNK] [UNK][UNK] (likedtr[UNK] wt [UNK][UNK] wt 
yot/gli2-/- [UNK] [UNK][UNK] [UNK] wt [UNK][UNK] [UNK][UNK] 
gli2 MO wt/[UNK] wt wt/[UNK] [UNK] wt/[UNK] wt 
gli2 MO→yot-/- wt/[UNK] (rescue) wt (rescue) wt (rescue) [UNK] wt/[UNK] (rescue) [UNK] (rescue) 
gli2 MO→dtr-/- nd [UNK][UNK] (likedtr[UNK] (like dtr[UNK] nd [UNK] 
yot-/+;dtr-/+ [UNK] [UNK][UNK]nd nd [UNK] [UNK] 
[UNK]

: reduced; [UNK][UNK]: strongly reduced; [UNK]: increased/expanded; di:diencephalon; tel: telencephalon; mb: midbrain; nd: not determined; vent:ventral; wt: wild type.

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