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Table 1.

gli1 MO injection into wild-type embryos phenocopies dtr nk2.2 defects

gli MO injectedVery strongdtr phenocopyPartial phenocopywt nk2.2Total
Control (6-13 ng) 150 (100%) 150 
0.2-1 ng 44 (43%) 58 (57%) 102 
2 ng 32 (60%) 14 (26%) 7 (13%) 53 
3 ng 38 (26%) 48 (33%) 33 (23%) 17 (12%) 146 
5-7 ng 37 (52%) 21 (30%) 13 (18%) 71 
11 ng 37 (76%) 12 (24%) 49 
gli MO injectedVery strongdtr phenocopyPartial phenocopywt nk2.2Total
Control (6-13 ng) 150 (100%) 150 
0.2-1 ng 44 (43%) 58 (57%) 102 
2 ng 32 (60%) 14 (26%) 7 (13%) 53 
3 ng 38 (26%) 48 (33%) 33 (23%) 17 (12%) 146 
5-7 ng 37 (52%) 21 (30%) 13 (18%) 71 
11 ng 37 (76%) 12 (24%) 49 

Very strong: nk2.2 extremely reduced in malformed embryos.

Partial phenocopy: nk2.2 reduced but not absent.

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