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Table 1.

bapx1 is required for the jaw joint

Joint region phenotype
Concentration of bapx1-MO (mg/ml)Percentages
Joint lossJoint+RAP lossNo BHSmall BH
Uninjected  0 (0/100) 0 (0/100) 
MO1 51 (108/213) 1 (2.5/213) 16 
 80 (147/183) 23 (42/183) 70 
MO2 2 (1/48) 0 (0/48) 
 88 (66/75) 23 (17/75) 48 52 
MO1+2 0.5 each 77 (51/66) 5 (3/66) 97 
 1.5 each 98 (59/60) 55 (33/60) 67 33 
Joint region phenotype
Concentration of bapx1-MO (mg/ml)Percentages
Joint lossJoint+RAP lossNo BHSmall BH
Uninjected  0 (0/100) 0 (0/100) 
MO1 51 (108/213) 1 (2.5/213) 16 
 80 (147/183) 23 (42/183) 70 
MO2 2 (1/48) 0 (0/48) 
 88 (66/75) 23 (17/75) 48 52 
MO1+2 0.5 each 77 (51/66) 5 (3/66) 97 
 1.5 each 98 (59/60) 55 (33/60) 67 33 

Animals were fixed at 4 days and Alcian stained, then scored in wholemounts. Both left and right sides of each animal were scored, and counted as half an animal. Joint loss animals lacked the joint, but had the cartilaginous retroarticular process (RAP) of Meckel's cartilage, whereas joint + RAP loss animals lacked both the joint and RAP. No animals were observed to lack the process yet have the joint. BH, basihyal.

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