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Table 1.

Migration descriptors determined from time-lapse images of cells in the scratch migration assay

	C–V median^{^*}	C+V median^{^*}	P value^{^*}	b3–V median^{^†}	b3+V median^{^†}	P value^{^†}
Tortuosity	9.47	2.57	<0.0001	5.53	5.20	0.834
Time lag for D/5 (seconds)	9.83	25.2	0.0030	15.9	10.3	0.108
Direction ± 9/12	1.5	0	<0.0001	0	0	0.099
Average speed (μm/second)	0.014	0.009	<0.0001	0.0092	0.0090	0.049
Velocity component (μm/second)	0.0014	0.0037	0.0012	0.0016	0.0013	0.502

	C–V median^{^*}	C+V median^{^*}	P value^{^*}	b3–V median^{^†}	b3+V median^{^†}	P value^{^†}
Tortuosity	9.47	2.57	<0.0001	5.53	5.20	0.834
Time lag for D/5 (seconds)	9.83	25.2	0.0030	15.9	10.3	0.108
Direction ± 9/12	1.5	0	<0.0001	0	0	0.099
Average speed (μm/second)	0.014	0.009	<0.0001	0.0092	0.0090	0.049
Velocity component (μm/second)	0.0014	0.0037	0.0012	0.0016	0.0013	0.502

Data from cells transfected with control scrambled siRNA

data from cells transfected with PLCβ3 siRNA. Each group represents data from at least 30 cells