Table 2.

tar*-mediated restoration of EB ganglia requires endoderm-derived Fgf3*

nfgSmall vLarge v
Transplant of GFP-positive wt cells into cas-MO 15 0 n/d 
Transplant of tar* cells into cas-MO 45 21 (47%) 7 (16%) 10 (22%) n/d 
Transplant of tar*+fgf3-MO1 cells into cas-MO§ 30 2 (7%) 2 (7%) 2 (7%) n/d 
nfgSmall vLarge v
Transplant of GFP-positive wt cells into cas-MO 15 0 n/d 
Transplant of tar* cells into cas-MO 45 21 (47%) 7 (16%) 10 (22%) n/d 
Transplant of tar*+fgf3-MO1 cells into cas-MO§ 30 2 (7%) 2 (7%) 2 (7%) n/d 

wt, wild type; f, facial ganglion; g, glossopharyngeal ganglion; v, vagal ganglion.

*

All phenotypes assessed by phox2a expression at 36 hpf.

Number of embryos in each treatment group.

Significantly larger than contralateral control, see Fig. 4D.

§

\(P{\ll}0.01\)
2 test) when compared to tar*transplants without fgf3-MO1.

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