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Table 2.

Sequences used in alignment and phylogeny

CD14 Human (Homo sapiens) – AAH10507, cow (Bos taurus)– BAA21517, water buffalo (Bubalus bubalis) – ABD97885,rabbit (Oryctolagus cuniculus) – BAA21770, horse (Equus callabus) – AAF08963, mouse (Mus musculus) –CAA32166, steppe mouse (Mus spicilegus) – BAB68587, sheep(Ovis aries) – CAJ90519, rat (Rattus norvegicus)– AAC35371, goat (Capra hircus) – ABE68725, big horned sheep (Ovis canadensis) – ABI95798, pig (Sus scrofa)– ABK32433 and short grey-tailed opossum (Monodelphis domestica) – XP_001377002. 
TLR1 Human – CAG38593, fugu (Takifugu rubripes) – AAW69368,mouse – NP_109607, pig – NP_001026945, zebrafish (Danio rerio) – AAQ91305, cow – NP_001039969 and chicken (Gallus gallus) – NP_001007489. 
TLR2 Fugu – AAW69370, zebrafish – AAQ91306, sheep – ABI58266,chicken – NP_989609, human – NP_003255, rat – NP_942064,mouse – NP_036035, cow – NP_776622 and pig – NP_998926. 
TLR3 Fugu – AAW69373, human – NP_003256, mouse – NP_569054, rat– NP_942086, zebrafish – NP_001013287, cow – CAH19227, pig– ABB92547 and chicken – XP001231987. 
TLR4 Tammar (Macropus eugenii) – gnl/ti/1457595886, human –AAI17423, rhesus monkey (Macaca mulatta) – AAX63196, orangutan(Pongo pygmaeus) – AAM18616, cow – ABH09760, water buffalo – ABH11655, sheep – ABI96901, goat – ABI96900, pig– AAT05612, horse – AAU95608 and cat (Felis catus)– NP_001009223. 
TLR5 Fugu – AAW69374, human – AAI09119, mouse – AAI25248, cow– ABC68311, pig – BAD91800, chicken – NP_001019757 and zebrafish – ABD16185. 
TLR6 Mouse – BAA78632, human – BAA78631, pig – NP_998925, cow– CAJ35083 and rat – NP_997487. 
TLR7 Fugu – AAW69375, human – AAQ88659, mouse – NP_573474,chicken – NP_001011688, zebrafish – AAQ91312 and cow –NP_001028933. 
TLR8 Fugu – AAW69379, human – AAQ88663, mouse – NP_573475, cow– NP_001029109 and pig – NP_999352. 
TLR9 Fugu – AAW69377, human – AAQ89443, mouse – NP_112455, cow– NP_898904, pig – NP_999123 and rat – NP_937764. 
TLR10 Human – AAQ88667, pig – NP_001025705 and cow – NP_001070386. 
CD14 Human (Homo sapiens) – AAH10507, cow (Bos taurus)– BAA21517, water buffalo (Bubalus bubalis) – ABD97885,rabbit (Oryctolagus cuniculus) – BAA21770, horse (Equus callabus) – AAF08963, mouse (Mus musculus) –CAA32166, steppe mouse (Mus spicilegus) – BAB68587, sheep(Ovis aries) – CAJ90519, rat (Rattus norvegicus)– AAC35371, goat (Capra hircus) – ABE68725, big horned sheep (Ovis canadensis) – ABI95798, pig (Sus scrofa)– ABK32433 and short grey-tailed opossum (Monodelphis domestica) – XP_001377002. 
TLR1 Human – CAG38593, fugu (Takifugu rubripes) – AAW69368,mouse – NP_109607, pig – NP_001026945, zebrafish (Danio rerio) – AAQ91305, cow – NP_001039969 and chicken (Gallus gallus) – NP_001007489. 
TLR2 Fugu – AAW69370, zebrafish – AAQ91306, sheep – ABI58266,chicken – NP_989609, human – NP_003255, rat – NP_942064,mouse – NP_036035, cow – NP_776622 and pig – NP_998926. 
TLR3 Fugu – AAW69373, human – NP_003256, mouse – NP_569054, rat– NP_942086, zebrafish – NP_001013287, cow – CAH19227, pig– ABB92547 and chicken – XP001231987. 
TLR4 Tammar (Macropus eugenii) – gnl/ti/1457595886, human –AAI17423, rhesus monkey (Macaca mulatta) – AAX63196, orangutan(Pongo pygmaeus) – AAM18616, cow – ABH09760, water buffalo – ABH11655, sheep – ABI96901, goat – ABI96900, pig– AAT05612, horse – AAU95608 and cat (Felis catus)– NP_001009223. 
TLR5 Fugu – AAW69374, human – AAI09119, mouse – AAI25248, cow– ABC68311, pig – BAD91800, chicken – NP_001019757 and zebrafish – ABD16185. 
TLR6 Mouse – BAA78632, human – BAA78631, pig – NP_998925, cow– CAJ35083 and rat – NP_997487. 
TLR7 Fugu – AAW69375, human – AAQ88659, mouse – NP_573474,chicken – NP_001011688, zebrafish – AAQ91312 and cow –NP_001028933. 
TLR8 Fugu – AAW69379, human – AAQ88663, mouse – NP_573475, cow– NP_001029109 and pig – NP_999352. 
TLR9 Fugu – AAW69377, human – AAQ89443, mouse – NP_112455, cow– NP_898904, pig – NP_999123 and rat – NP_937764. 
TLR10 Human – AAQ88667, pig – NP_001025705 and cow – NP_001070386. 

Accession numbers (GenBank) are given after each species name

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