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Table 2.

Genes with a higher expression in wild-type cells (more than twofold)

Gene or ORFa WT/mut ratiob Functionc
CTS1  3.9   Endochitinase; cell separation.  
DSE2  3.8   Protein involved in cell separation.  
FIT2  3.6   GPI-CWP; facilitator of iron transport.  
FIT3  3.0   GPI-CWP; facilitator of iron transport.  
RNR2  3.0   Ribonucleotide reductase.  
TIM54  2.8   Mitochondrial inner membrane protein.  
HTA2  2.7   Histone H2A.  
HTB2  2.6   Histone H2B.  
SML1  2.5   Protein that negatively affects dNTP pools.  
RNR4  2.4   Ribonucleotide reductase, small subunit.  
CUP1  2.4   Metallothionein.  
YMR009w  2.4   None known.  
YOL014w  2.4   None known.  
CPR6  2.3   Cyclophilin.  
ENG1/DSE4  2.1   Endo-1,3-β-glucanase; involved in cell separation.  
IMD4  2.1   Protein with similarity to inosine-5′-monophosphate dehydrogenase.  
SCC3  2.1   Cyclophilin of the endoplasmic reticulum membrane.  
SSA1  2.1   Cytoplasmic chaperone and heat shock protein of the HSP70 family.  
SSA4  2.1   Protein chaperone of the HSP70 family.  
SSA2  2.0   Cytoplasmic protein chaperone of the HSP70 family.  
RHK1  2.0   Mannosyltransferase involved in N-glycosylation.  
AHA1  2.0   Activator of heat-shock protein 90 ATPase.  
Gene or ORFa WT/mut ratiob Functionc
CTS1  3.9   Endochitinase; cell separation.  
DSE2  3.8   Protein involved in cell separation.  
FIT2  3.6   GPI-CWP; facilitator of iron transport.  
FIT3  3.0   GPI-CWP; facilitator of iron transport.  
RNR2  3.0   Ribonucleotide reductase.  
TIM54  2.8   Mitochondrial inner membrane protein.  
HTA2  2.7   Histone H2A.  
HTB2  2.6   Histone H2B.  
SML1  2.5   Protein that negatively affects dNTP pools.  
RNR4  2.4   Ribonucleotide reductase, small subunit.  
CUP1  2.4   Metallothionein.  
YMR009w  2.4   None known.  
YOL014w  2.4   None known.  
CPR6  2.3   Cyclophilin.  
ENG1/DSE4  2.1   Endo-1,3-β-glucanase; involved in cell separation.  
IMD4  2.1   Protein with similarity to inosine-5′-monophosphate dehydrogenase.  
SCC3  2.1   Cyclophilin of the endoplasmic reticulum membrane.  
SSA1  2.1   Cytoplasmic chaperone and heat shock protein of the HSP70 family.  
SSA4  2.1   Protein chaperone of the HSP70 family.  
SSA2  2.0   Cytoplasmic protein chaperone of the HSP70 family.  
RHK1  2.0   Mannosyltransferase involved in N-glycosylation.  
AHA1  2.0   Activator of heat-shock protein 90 ATPase.  
a

ORF, open reading frame

b

This is the mean of the normalized ratios of expression in the wild type and mutant strains (three independent experiments)

c

According to Saccharomyces Genome Database

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