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Table 1.

Effect of T3 or GC-1 treatment on body parameters, heart rate,resting metabolic rate, and serum levels of cholesterol and free iodothyronines

ParameterCHH+T3H+GC-1
Body mass (g) 267.0±4.1 276.1±6.0 247.3±8.2a,b 270.4±7.3c 
Heart mass (mg) 670±20 550±10a 790±50a,b 640±30c 
Heart mass/body mass (mg g–12.50±0.04 2.01±0.03a 3.23±0.15a,b 2.34±0.06b,c 
Heart rate (beats min–1357±12 278±9a 534±12a,b 367±7b,c 
RMR (l O2 kg–1 h–11.10±0.02 1.01±0.03a 1.57±0.01a,b 1.12±0.03b,c 
Cholesterol (mg dl–146.6±1.4 63.7±1.6a 41.8±1.7b 46.6±1.6b 
FT3 (pg dl–1301±24 25.5±5.1a 571.0±57.5a,b 26.4±4.9a,c 
FT4 (ng dl–11.45±0.09 0.33±0.04a 0.39±0.04a 0.30±0.03a 
ParameterCHH+T3H+GC-1
Body mass (g) 267.0±4.1 276.1±6.0 247.3±8.2a,b 270.4±7.3c 
Heart mass (mg) 670±20 550±10a 790±50a,b 640±30c 
Heart mass/body mass (mg g–12.50±0.04 2.01±0.03a 3.23±0.15a,b 2.34±0.06b,c 
Heart rate (beats min–1357±12 278±9a 534±12a,b 367±7b,c 
RMR (l O2 kg–1 h–11.10±0.02 1.01±0.03a 1.57±0.01a,b 1.12±0.03b,c 
Cholesterol (mg dl–146.6±1.4 63.7±1.6a 41.8±1.7b 46.6±1.6b 
FT3 (pg dl–1301±24 25.5±5.1a 571.0±57.5a,b 26.4±4.9a,c 
FT4 (ng dl–11.45±0.09 0.33±0.04a 0.39±0.04a 0.30±0.03a 

Values are means ± s.e.m. For each value eight rats were used

RMR, resting metabolic rate; FT3 and FT4, serum level of free triiodothyronine and thyroxine, respectively; C, control euthyroid rats; H, hypothyroid rats; H+T3, hypothyroid T3-treated rats; H+GC-1, hypothyroid GC-1-treated rats

a

Significant vs C rats

b

significant vs H rats

c

significant vs H+T3 rats. The level of significance was chosen as P<0.05

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