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Table 1.

Comparison of important properties of some model organisms

OrganismGenome?Generation time?Cost/year?Transgenics?Targeted mutagenesis?Tissue specific?Available mutants?Physiology?
Human Yes 16–40 years Very high No! No! No Yes Very limited 
Mouse Yes 3 months Very high Yes Yes Yes Many Yes 
Zebra fish End 2008 3–4 months Moderate No No Yes Yes Some 
Drosophila Yes 1 week Very low Yes Yes Yes Many Some 
Caenorhabditis Yes 4 days Very low Yes Yes Yes Many Very little 
Saccharomyces Yes 90 min Very low Yes Yes Yes Many Not as we know it 
Escherichia Yes 20 min Very low Yes Yes Yes Many Not as we know it 
OrganismGenome?Generation time?Cost/year?Transgenics?Targeted mutagenesis?Tissue specific?Available mutants?Physiology?
Human Yes 16–40 years Very high No! No! No Yes Very limited 
Mouse Yes 3 months Very high Yes Yes Yes Many Yes 
Zebra fish End 2008 3–4 months Moderate No No Yes Yes Some 
Drosophila Yes 1 week Very low Yes Yes Yes Many Some 
Caenorhabditis Yes 4 days Very low Yes Yes Yes Many Very little 
Saccharomyces Yes 90 min Very low Yes Yes Yes Many Not as we know it 
Escherichia Yes 20 min Very low Yes Yes Yes Many Not as we know it 
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