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Table 1.

Experiment 1: effects of maximal workload on main characteristics in control (C) and activity-selected mice (S)

Baseline
Maximal workload
P values
C (N=8)S (N=8)C (N=8)S (N=8)d.f.LineTreatmentPower of analysis
Wheel-running activity (km day-111.5±1.2 14.7±0.8 23.2±1.4 23.4±1.4 1,14 0.29 <0.001 0.22/0.24 
Body mass (g) 30.9±0.5 30.6±0.5 26.0±0.3 25.5±0.5 1,14 0.82 <0.001 0.98/0.99 
Food intake (g day-15.7±0.1 6.0±0.2 4.6±0.3 4.6±0.2 1,14 0.44 <0.001 0.52/0.17 
Mass-specific food intake (g g-1 day-10.20±0.01 0.18±0.01 0.18±0.01 1,14 0.38 0.43 0.96/0.54 
Baseline
Maximal workload
P values
C (N=8)S (N=8)C (N=8)S (N=8)d.f.LineTreatmentPower of analysis
Wheel-running activity (km day-111.5±1.2 14.7±0.8 23.2±1.4 23.4±1.4 1,14 0.29 <0.001 0.22/0.24 
Body mass (g) 30.9±0.5 30.6±0.5 26.0±0.3 25.5±0.5 1,14 0.82 <0.001 0.98/0.99 
Food intake (g day-15.7±0.1 6.0±0.2 4.6±0.3 4.6±0.2 1,14 0.44 <0.001 0.52/0.17 
Mass-specific food intake (g g-1 day-10.20±0.01 0.18±0.01 0.18±0.01 1,14 0.38 0.43 0.96/0.54 

Wheel-running activity, body mass and food intake during baseline and at maximal workload in activity-selected mice and random-bred controls. Values given are mean ± s.e.m. Repeated-measures ANOVA with line (C versus S) as between-subjects factor and treatment (baseline versus workload) as within-subjects factor were performed. Interactions between line and treatment was never significant and are therefore not shown in the Table. Significant results are highlighted in bold

d.f., degrees of freedom; N, sample size

A power analysis for the two-tailed t-tests was performed at a fixed effect size of 10% difference between the lines using the Gpower program(Faul and Erdfelder, 1992); we entered mean values and s.e.m. measured for control mice and calculated the power when the mean for the selected mice differed from the controls by 10%. The values in the Table represent the power for the comparison between C and S mice at baseline and workload, respectively

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