Number of lordotic tadpoles in relation to the age at onset of microgravity and the period of μg-exposure during the mission
. | SMM-06 . | . | . | Andromède . | . | . | D-21 . | . | . | Andromède . | . | . | SMM-062 . | . | . | SMM-063 . | . | . | SL-J4 . | . | . | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | STS-84 . | . | . | Soyuz-taxi/ISS . | . | . | STS-55 . | . | . | Soyuz-taxi/ISS . | . | . | STS-84 . | . | . | STS-84 . | . | . | STS-47 . | . | . | ||||||||||||||
Year . | 1997 . | . | . | 2001 . | . | . | 1993 . | . | . | 2001 . | . | . | 1997 . | . | . | 1997 . | . | . | 1994 . | . | . | ||||||||||||||
Stage at launch . | 25-28 . | . | . | 26-27 . | . | . | 33-36 . | . | . | 45 . | . | . | 42-43 . | . | . | 25-28 . | . | . | Fertil. in μg . | . | . | ||||||||||||||
Duration (days) . | 9 . | . | . | 9 . | . | . | 10 . | . | . | 9 . | . | . | 9 . | . | . | 9 . | . | . | 7 . | . | . | ||||||||||||||
Days of μg . | Whole mission . | . | . | Whole mission . | . | . | Whole mission . | . | . | Whole mission . | . | . | FD5-FD9 . | . | . | FD1-FD5 . | . | . | FD2-FD7 . | . | . | ||||||||||||||
. | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | ||||||||||||||
First observation | 9 | 25 | 26.5 | 14 | 4 | 77.8 | 3 | 16 | 15.8 | 9 | 3 | 75.0 | 15 | 13 | 53.6 | 32 | 0 | 100 | 100 | ||||||||||||||||
Mean stage | 47.1 | 47.0 | 46.3 | 46.0 | 45.0 | 44.9 | 47.0 | 46.7 | 47.2 | 47.0 | 47.1 | − | 46 | ||||||||||||||||||||||
Days after 0g | 1-4 | 2-4 | 2-6 | 2-4 | 1-4 | 1-4 | Post-flight H/O | ||||||||||||||||||||||||||||
Second observation | 22 | 7 | 75.9 | 3 | 3 | 50.0 | 20 | 3 | 87.0 | 29 | 0 | 100 | |||||||||||||||||||||||
Mean stage | 48.3 | 47.7 | 46.5 | 46.0 | 48.6 | 47.3 | 48.5 | − | |||||||||||||||||||||||||||
Days after 0g | 8-11 | 9-12 | 8-11 | 8-11 | |||||||||||||||||||||||||||||||
Third observation5 | 27 | 1 | 96.4 | 22 | 1 | 95.7 | 29 | 0 | 100 | ||||||||||||||||||||||||||
Days after 0g | 14 | 14 | 14 |
. | SMM-06 . | . | . | Andromède . | . | . | D-21 . | . | . | Andromède . | . | . | SMM-062 . | . | . | SMM-063 . | . | . | SL-J4 . | . | . | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | STS-84 . | . | . | Soyuz-taxi/ISS . | . | . | STS-55 . | . | . | Soyuz-taxi/ISS . | . | . | STS-84 . | . | . | STS-84 . | . | . | STS-47 . | . | . | ||||||||||||||
Year . | 1997 . | . | . | 2001 . | . | . | 1993 . | . | . | 2001 . | . | . | 1997 . | . | . | 1997 . | . | . | 1994 . | . | . | ||||||||||||||
Stage at launch . | 25-28 . | . | . | 26-27 . | . | . | 33-36 . | . | . | 45 . | . | . | 42-43 . | . | . | 25-28 . | . | . | Fertil. in μg . | . | . | ||||||||||||||
Duration (days) . | 9 . | . | . | 9 . | . | . | 10 . | . | . | 9 . | . | . | 9 . | . | . | 9 . | . | . | 7 . | . | . | ||||||||||||||
Days of μg . | Whole mission . | . | . | Whole mission . | . | . | Whole mission . | . | . | Whole mission . | . | . | FD5-FD9 . | . | . | FD1-FD5 . | . | . | FD2-FD7 . | . | . | ||||||||||||||
. | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | N . | L . | N% . | ||||||||||||||
First observation | 9 | 25 | 26.5 | 14 | 4 | 77.8 | 3 | 16 | 15.8 | 9 | 3 | 75.0 | 15 | 13 | 53.6 | 32 | 0 | 100 | 100 | ||||||||||||||||
Mean stage | 47.1 | 47.0 | 46.3 | 46.0 | 45.0 | 44.9 | 47.0 | 46.7 | 47.2 | 47.0 | 47.1 | − | 46 | ||||||||||||||||||||||
Days after 0g | 1-4 | 2-4 | 2-6 | 2-4 | 1-4 | 1-4 | Post-flight H/O | ||||||||||||||||||||||||||||
Second observation | 22 | 7 | 75.9 | 3 | 3 | 50.0 | 20 | 3 | 87.0 | 29 | 0 | 100 | |||||||||||||||||||||||
Mean stage | 48.3 | 47.7 | 46.5 | 46.0 | 48.6 | 47.3 | 48.5 | − | |||||||||||||||||||||||||||
Days after 0g | 8-11 | 9-12 | 8-11 | 8-11 | |||||||||||||||||||||||||||||||
Third observation5 | 27 | 1 | 96.4 | 22 | 1 | 95.7 | 29 | 0 | 100 | ||||||||||||||||||||||||||
Days after 0g | 14 | 14 | 14 |
FD, flight day; N, normal shape; L, lordotic shape; N%, percentage of normal tadpoles.
1Data from the rVOR component of the STATEX project; 2after exposure to 1g in the BIORACK centrifuge for 4 days; 3after FD5, exposure to 1g in the BIORACK centrifuge; 4fertilization in orbit not before 34 h after launch,stages immediately after handover (H/O) of the samples at the landing day[data from the Japanese Spacelab mission SL-J(Souza et al., 1995)]; 5stages were not determined at 14 days after landing.
Lordotic animals were also observed in two other experiments with pre-flight fertilized eggs of Xenopus (stage 25 at launch). One of them was performed on the Russian Cosmos 2229 satellite (11.5-daysμ g), the other on the Japanese Spacelab mission SL-J(STS-47). These experiments are not included in the table because the authors(Snetkova et al., 1995) gave no numbers of lordotic tadpoles. Stages are defined according to published tables (Nieuwkoop and Faber,1967).