Table 1.

Summary of protective properties of osmolytes through metabolic reactions

Cytoprotective propertyCompatible solutes in nature
Antioxidation Hypotaurine; DMSP; polyols (e.g. water-stressed plant) 
Redox balancing, hypoxia Proline, β-alanine betaine, glycerol (e.g. Dunaliella alga) 
Sulphide detoxification/storage Hypotaurine (e.g. hydrothermal vent tubeworm, Riftia
Sulphate detoxification Choline-O-sulphate (e.g. mangrove plant) 
Energy reserve Glucose, trehalose, etc. (e.g. frozen wood frog) 
Predator repellent DMSP, trans-hydroxyprolinebetaine (e.g. diatom) 
Ca2+ modulation Taurine? (e.g. mammalian neuron) 
Cytoprotective propertyCompatible solutes in nature
Antioxidation Hypotaurine; DMSP; polyols (e.g. water-stressed plant) 
Redox balancing, hypoxia Proline, β-alanine betaine, glycerol (e.g. Dunaliella alga) 
Sulphide detoxification/storage Hypotaurine (e.g. hydrothermal vent tubeworm, Riftia
Sulphate detoxification Choline-O-sulphate (e.g. mangrove plant) 
Energy reserve Glucose, trehalose, etc. (e.g. frozen wood frog) 
Predator repellent DMSP, trans-hydroxyprolinebetaine (e.g. diatom) 
Ca2+ modulation Taurine? (e.g. mammalian neuron) 
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