Skip to Main Content
Table 1.

Effect of Anoga-DH44 and Anoga-DH31 on fluid secretion and ion (Na+ and K+) transport by Malpighian tubules of the yellow fever mosquito (Ae. aegypti)

Fluid secretion (nl min-1)[Na+]:[K+]K+ transport (pmol min-1)Na+ transport (pmol min-1)
Anoga-DH44 and 8-bromo-cyclic AMP (N=6)     
    Basal 0.29±0.10 0.89±0.21a 35.4±15.8b 16.6±4.1 
    Anoga-DH44 (1 μmol 1-10.78±0.17 0.96±0.25a 74.4±20.7b,c 50.9±11.1 
    + cAMP (1 mmol 1-12.99±0.47 3.40±0.63 137.6±35.7c 383.8±64.7 
Anoga-DH31 and 8-bromo-cyclic AMP (N=6)     
    Basal 0.56±0.10 0.96±0.18 57.5±10.2e 48.1±9.2 
    Anoga-DH31 (1 μmol 1-13.57±0.51d 4.33±0.34 123.9±22.3f 523.1±75.0g 
    + cAMP (1 mmol 1-13.28±0.38d 6.22±0.41 82.9±14.2e,f 495.7±59.3g 
Anoga-DH44 and Anoga-DH31 (N=8)     
    Basal 0.28±0.06 0.45±0.04h 38.1±8.9 16.2±2.8 
    Anoga-DH44 (1 μmol 1-10.73±0.13 0.39±0.03h 99.4±18.2i 38.4±8.2 
    Anoga-DH31 (1 μmol 1-12.09±0.25 2.27±0.20 120.0±12.8i 259.1±35.6 
Fluid secretion (nl min-1)[Na+]:[K+]K+ transport (pmol min-1)Na+ transport (pmol min-1)
Anoga-DH44 and 8-bromo-cyclic AMP (N=6)     
    Basal 0.29±0.10 0.89±0.21a 35.4±15.8b 16.6±4.1 
    Anoga-DH44 (1 μmol 1-10.78±0.17 0.96±0.25a 74.4±20.7b,c 50.9±11.1 
    + cAMP (1 mmol 1-12.99±0.47 3.40±0.63 137.6±35.7c 383.8±64.7 
Anoga-DH31 and 8-bromo-cyclic AMP (N=6)     
    Basal 0.56±0.10 0.96±0.18 57.5±10.2e 48.1±9.2 
    Anoga-DH31 (1 μmol 1-13.57±0.51d 4.33±0.34 123.9±22.3f 523.1±75.0g 
    + cAMP (1 mmol 1-13.28±0.38d 6.22±0.41 82.9±14.2e,f 495.7±59.3g 
Anoga-DH44 and Anoga-DH31 (N=8)     
    Basal 0.28±0.06 0.45±0.04h 38.1±8.9 16.2±2.8 
    Anoga-DH44 (1 μmol 1-10.73±0.13 0.39±0.03h 99.4±18.2i 38.4±8.2 
    Anoga-DH31 (1 μmol 1-12.09±0.25 2.27±0.20 120.0±12.8i 259.1±35.6 

Values are means ± s.e.m. for the number of determinations shown in parentheses. Identical letters indicate values that do not differ significantly (P>0.05).

Close Modal

or Create an Account

Close Modal
Close Modal