The Company of Biologists

Table 3.

Lactate dehydrogenase isozyme activities from Ochotona princeps residing at 3350 m, Ochotona collaris residing at 1070 m,Ochotona hyperborea residing at sea level and laboratory rabbits(Oryctolagus cuniculus)

	Heart	Diaphragm	Vastus	Gastrocnemius	Soleus
H-LDH activity
O. princeps	399.85±13.27^a	428.43±14.24^a	565.57±17.15^a	689.75±36.46^a	886.24±46.33^a
O. collaris	162.24±8.17^b	181.65±14.33^b	245.61±28.39^b	245.55±17.35^b	229.59±22.36^b
O. hyperborea	109.31±14.08^c	—	—	—	—
Rabbit	147.48±12.11^b	407.96±9.85^c	161.38±84.64^c	422.54±11.94^c	128.25±23.56^c
M-LDH activity
O. princeps	5.97±0.20^a	157.62±15.86^a	453.60±21.61^a	537.29±32.73^a	256.16±49.90^a
O. collaris	10.54±0.53^b	101.00±3.83^b	373.94±46.67^b	310.10±41.31^b	273.06±44.59^a
O. hyperborea	16.39±2.59^c	—	—	—	—
Rabbit	4.02±0.54^d	128.10±5.05^c	959.69±130.09^c	529.99±13.66^a	40.57±4.56^b

	Heart	Diaphragm	Vastus	Gastrocnemius	Soleus
H-LDH activity
O. princeps	399.85±13.27^a	428.43±14.24^a	565.57±17.15^a	689.75±36.46^a	886.24±46.33^a
O. collaris	162.24±8.17^b	181.65±14.33^b	245.61±28.39^b	245.55±17.35^b	229.59±22.36^b
O. hyperborea	109.31±14.08^c	—	—	—	—
Rabbit	147.48±12.11^b	407.96±9.85^c	161.38±84.64^c	422.54±11.94^c	128.25±23.56^c
M-LDH activity
O. princeps	5.97±0.20^a	157.62±15.86^a	453.60±21.61^a	537.29±32.73^a	256.16±49.90^a
O. collaris	10.54±0.53^b	101.00±3.83^b	373.94±46.67^b	310.10±41.31^b	273.06±44.59^a
O. hyperborea	16.39±2.59^c	—	—	—	—
Rabbit	4.02±0.54^d	128.10±5.05^c	959.69±130.09^c	529.99±13.66^a	40.57±4.56^b

Values are means ± S.E.M., measured in μmol substrate converted g^-1 wet tissue min^-1. Statistical analyses were performed to compare activities of each enzyme between species within each tissue. Values within each column which do not have the same superscript letter differ significantly (P<0.05) as determined by analysis of variance and Scheffe's multiple range test. N=3 for all species.

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