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Table 1.

The path of oxygen

Model 1 assumes four key processes: 
1. Convection: air into the lung. 
2. Diffusion: O2 transfer from aleveoli to pulmonary capillaries. 
3. Convection: heart and circulatory transfer of O2 (+ carbon metabolites and end products) to various tissues and organs. 
4. Diffusion: O2 transfer from capillary blood to tissue intracellular milieu; CO2 and metabolite exchange. 
Model 2 adds: 
5. Convection: intracellular circulatory O2 transfer to mitochondria + numerous substrates to numerous enzymes in cytosolic pathways. 
6. Diffusion: final O2 transfer to cytochrome oxidase sinks (and final enzyme-substrate encounter for cytosolic pathways). 
Model 1 assumes four key processes: 
1. Convection: air into the lung. 
2. Diffusion: O2 transfer from aleveoli to pulmonary capillaries. 
3. Convection: heart and circulatory transfer of O2 (+ carbon metabolites and end products) to various tissues and organs. 
4. Diffusion: O2 transfer from capillary blood to tissue intracellular milieu; CO2 and metabolite exchange. 
Model 2 adds: 
5. Convection: intracellular circulatory O2 transfer to mitochondria + numerous substrates to numerous enzymes in cytosolic pathways. 
6. Diffusion: final O2 transfer to cytochrome oxidase sinks (and final enzyme-substrate encounter for cytosolic pathways). 
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