Cardiovascular defects in Dvl2-/- andDvl1-/-;Dvl2-/- embryos
| Abnormality . | Wild type . | Dvl2+/- . | Dvl2-/- . | Dvl1-/-;Dvl2-/- . |
|---|---|---|---|---|
| Double outlet right ventricle | 0 | 0 | 6 | 1 |
| Transposition of the great arteries | 0 | 0 | 1 | 1 |
| Persistent truncus arterioisis | 0 | 0 | 1 | 1 |
| Normal | 16/16 | 36/36 | 8/16 | 5/8* |
| Abnormality . | Wild type . | Dvl2+/- . | Dvl2-/- . | Dvl1-/-;Dvl2-/- . |
|---|---|---|---|---|
| Double outlet right ventricle | 0 | 0 | 6 | 1 |
| Transposition of the great arteries | 0 | 0 | 1 | 1 |
| Persistent truncus arterioisis | 0 | 0 | 1 | 1 |
| Normal | 16/16 | 36/36 | 8/16 | 5/8* |
Two embryos had body wall defects but normal cardiac development.