Recovery of conceptuses from intercross matings of TC/+ mice
| . | Age . | . | . | . | . | . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype . | ∼6.75 dpc n (%) . | ∼7.5 dpc n (%) . | ∼8.0 dpc n (%) . | ∼8.5 dpc n (%) . | ∼9.0 dpc n (%) . | ∼9.5 dpc n (%) . | ∼10.5 dpc n (%) . | ∼13.5 dpc n (%) . | |||||||
| +/+ | 14 (25.0) | 31 (22.5) | 123 (25.7) | 31 (23.8) | 7 (31.8) | 3 (27.3) | 6 (31.6) | 4 (20.0) | |||||||
| TC/+ | 24 (42.9) | 68 (49.3) | 234 (49.0) | 56 (43.1) | 8 (36.4) | 7 (63.6) | 8 (42.1) | 8 (40.0) | |||||||
| TC/TC | 13 (23.2) | 32 (23.2) | 96 (20.1) | 38 (29.2) | 7 (31.8) | 1 (9.1) | 0 | 0 | |||||||
| Resorptions | 5 (8.9) | 7 (5.0) | 25 (5.2) | 5 (3.8) | 0 | 0 | 5* (26.3) | 8† (40.0) | |||||||
| Number of litters | 6 | 17 | 54 | 20 | 3 | 3 | 2 | 2 | |||||||
| . | Age . | . | . | . | . | . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype . | ∼6.75 dpc n (%) . | ∼7.5 dpc n (%) . | ∼8.0 dpc n (%) . | ∼8.5 dpc n (%) . | ∼9.0 dpc n (%) . | ∼9.5 dpc n (%) . | ∼10.5 dpc n (%) . | ∼13.5 dpc n (%) . | |||||||
| +/+ | 14 (25.0) | 31 (22.5) | 123 (25.7) | 31 (23.8) | 7 (31.8) | 3 (27.3) | 6 (31.6) | 4 (20.0) | |||||||
| TC/+ | 24 (42.9) | 68 (49.3) | 234 (49.0) | 56 (43.1) | 8 (36.4) | 7 (63.6) | 8 (42.1) | 8 (40.0) | |||||||
| TC/TC | 13 (23.2) | 32 (23.2) | 96 (20.1) | 38 (29.2) | 7 (31.8) | 1 (9.1) | 0 | 0 | |||||||
| Resorptions | 5 (8.9) | 7 (5.0) | 25 (5.2) | 5 (3.8) | 0 | 0 | 5* (26.3) | 8† (40.0) | |||||||
| Number of litters | 6 | 17 | 54 | 20 | 3 | 3 | 2 | 2 | |||||||
All genotypes were confirmed by PCR. For all stages the expected percentage of +/+, TC/+ and TC/TC conceptuses was 25%, 50% and 25%, respectively. Where possible (from ∼10.5-13.5 dpc),resorbing conceptuses were genotyped. Death of the conceptus was defined as absence of heart beat.
One TC/+ conceptus was dead and resorbing; all other dead, resorbing conceptuses were TC/TC.
Two TC/+ conceptuses were dead and resorbing;all other dead, resorbing conceptuses were TC/TC.