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Table 1.

Inhibition of SDF-2 production upon addition of anti-TagC antibodies or ABC inhibitors

AdditionsSDF-2 production
None No 
0.1 pM SDF-2 Yes 
0.1 pM SDF-2 + anti TagC No 
10 nM GABA + anti TagC No 
0.1 pM SDF-2 + 2 mM vanadate No 
10 nM GABA + 2 mM vanadate No 
0.1 pM SDF-2 + 100 μM verapamil No 
10 nM GABA + 100 μM verapamil No 
0.1 pM SDF-2 + 200 μM corticosterone No 
10 nM GABA + 200 μM corticosterone No 
AdditionsSDF-2 production
None No 
0.1 pM SDF-2 Yes 
0.1 pM SDF-2 + anti TagC No 
10 nM GABA + anti TagC No 
0.1 pM SDF-2 + 2 mM vanadate No 
10 nM GABA + 2 mM vanadate No 
0.1 pM SDF-2 + 100 μM verapamil No 
10 nM GABA + 100 μM verapamil No 
0.1 pM SDF-2 + 200 μM corticosterone No 
10 nM GABA + 200 μM corticosterone No 

Developed KP cells were treated with the various compounds and the supernatants collected after 1 hour, serially diluted and added to test KP cells.

`Yes' indicates at least 5000 units of SDF-2 per 103 cells; `No'indicates fewer than 10 units of SDF-2 per 103 cells.

All experiments were repeated at least three times.

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