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Table 3.

Quantification of ureteric tips loss in Wnt11-/-kidneys

Number of ureteric tipsWild type(%) (n=57)Wnt11-/-(%) (n=11)
42 
49 
64 
36 
Number of ureteric tipsWild type(%) (n=57)Wnt11-/-(%) (n=11)
42 
49 
64 
36 

Ureteric tips from E12.5 wild-type and Wnt11-/- kidneys hybridized with Ret antisense probe were counted. The percentage of kidneys (n=57 for wild type, 11 for mutant) with eight, seven, six,five or four tips is shown. Wnt11-/- kidneys show a statistically significant (P<0.001) difference from wild-type frequencies for the distribution of ureteric tips.

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