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Table 1.

Representation of the different forebrain phenotypes observed in stage 19/20 VAD quail embryos

PhenotypeEmbryos with phenotype (%)
Single uncleaved vesicle 100 
Lack of cephalic flexure 100 
Telencephalon  
Absent or very severely affected* 11 
Severely affected 77 
Moderately affected 12 
Normal 
Diencephalon  
No zli 100 
Ectopic ridges§ 70 
Enlarged§ 70 
Normal 30 
Eyes  
No eyes 
Right eye smaller 53 
Left eye smaller 23 
Normal eyes 23 
Nasal pits  
None 15 
No right 48 
No left 29 
Normal 
PhenotypeEmbryos with phenotype (%)
Single uncleaved vesicle 100 
Lack of cephalic flexure 100 
Telencephalon  
Absent or very severely affected* 11 
Severely affected 77 
Moderately affected 12 
Normal 
Diencephalon  
No zli 100 
Ectopic ridges§ 70 
Enlarged§ 70 
Normal 30 
Eyes  
No eyes 
Right eye smaller 53 
Left eye smaller 23 
Normal eyes 23 
Nasal pits  
None 15 
No right 48 
No left 29 
Normal 

Sixty-six VAD embryos were examined.

*

Indicates reduction of more than 80%.

Indicates reduction between 50% and 80%.

Indicates reduction of 50% or less than 50%.

§

These two abnormalities can be detected in different embryos.

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