The Company of Biologists

Table 1.

Representation of the different forebrain phenotypes observed in stage 19/20 VAD quail embryos

Phenotype	Embryos with phenotype (%)
Single uncleaved vesicle	100
Lack of cephalic flexure	100
Telencephalon
Absent or very severely affected^*	11
Severely affected^{^†}	77
Moderately affected^{^‡}	12
Normal	0
Diencephalon
No zli	100
Ectopic ridges^{^§}	70
Enlarged^{^§}	70
Normal	30
Eyes
No eyes	1
Right eye smaller	53
Left eye smaller	23
Normal eyes	23
Nasal pits
None	15
No right	48
No left	29
Normal	8

Phenotype	Embryos with phenotype (%)
Single uncleaved vesicle	100
Lack of cephalic flexure	100
Telencephalon
Absent or very severely affected^*	11
Severely affected^{^†}	77
Moderately affected^{^‡}	12
Normal	0
Diencephalon
No zli	100
Ectopic ridges^{^§}	70
Enlarged^{^§}	70
Normal	30
Eyes
No eyes	1
Right eye smaller	53
Left eye smaller	23
Normal eyes	23
Nasal pits
None	15
No right	48
No left	29
Normal	8

Sixty-six VAD embryos were examined.

Indicates reduction of more than 80%.

Indicates reduction between 50% and 80%.

Indicates reduction of 50% or less than 50%.

These two abnormalities can be detected in different embryos.