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Table 1.

Genotypes of embryos from Tbx4 heterozygous intercrosses at different embryonic ages

Age (dpc)
AlleleGenotype8.08.59.09.510.511.011.513.5Total §
Tbx4tm1Pa +/+ 56 29 87 191 
 +/- 127 45 13 20 176 399 
 -/- 60 18 84* 5 3 2 188 
Tbx4tm1.1Pa +/+ nd 36 nd nd 53 
 +/- 15 nd 15 88 nd nd 126 
 -/- 14 nd 48 nd 3 nd 76 
Age (dpc)
AlleleGenotype8.08.59.09.510.511.011.513.5Total §
Tbx4tm1Pa +/+ 56 29 87 191 
 +/- 127 45 13 20 176 399 
 -/- 60 18 84* 5 3 2 188 
Tbx4tm1.1Pa +/+ nd 36 nd nd 53 
 +/- 15 nd 15 88 nd nd 126 
 -/- 14 nd 48 nd 3 nd 76 
*

Approximately 20% of -/- embryos dissected before 1.00 pm were dead. 53% of-/- embryos dissected after 1.00 pm were dead.

Approximately 20% of -/- embryos dissected before 1.00 pm were dead.

Embryos were dead and degenerating. Genotypes were obtained from the yolk sac or the embryonic part of the placenta.

§

No significant differences from Mendelian ratios of inheritance were found for Tbx4tm1Pa (X2=0.54, P>0.25) and Tbx4tm1.1Pa (X2=4.18, P>0.15). nd,note done.

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