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Table 1.

p53 and PIK3CA status of the cancer cell lines

Cell lines p53 mutation p53 references PIK3CA copy number PIK3CA references
A2780   None   (Brown et al., 1993)   2   (W. L. Kuo and J. W. Gray, personal communication)  
CaoV3   Nonsense   (Yaginuma and Westphal, 1992)   6.7   (Shayesteh et al., 1999)  
SKOV3   Null   (Yaginuma and Westphal, 1992)   3   (Shayesteh et al., 1999)  
OVCAR3   Missense   (Yaginuma and Westphal, 1992)   6.1   (Shayesteh et al., 1999)  
OVCAR4   None   (O'Connor et al., 1997)   ?   N/A  
OVCAR5   Null   (O'Connor et al., 1997)   3.6   (W. L. Kuo and J. W. Gray, personal communication)  
OVCAR8   Missense   (O'Connor et al., 1997)   1.6   (W. L. Kuo and J. W. Gray, personal communication)  
MCF7   None   (Takahashi et al., 1993)   2   (Shayesteh et al., 1999)  
Cell lines p53 mutation p53 references PIK3CA copy number PIK3CA references
A2780   None   (Brown et al., 1993)   2   (W. L. Kuo and J. W. Gray, personal communication)  
CaoV3   Nonsense   (Yaginuma and Westphal, 1992)   6.7   (Shayesteh et al., 1999)  
SKOV3   Null   (Yaginuma and Westphal, 1992)   3   (Shayesteh et al., 1999)  
OVCAR3   Missense   (Yaginuma and Westphal, 1992)   6.1   (Shayesteh et al., 1999)  
OVCAR4   None   (O'Connor et al., 1997)   ?   N/A  
OVCAR5   Null   (O'Connor et al., 1997)   3.6   (W. L. Kuo and J. W. Gray, personal communication)  
OVCAR8   Missense   (O'Connor et al., 1997)   1.6   (W. L. Kuo and J. W. Gray, personal communication)  
MCF7   None   (Takahashi et al., 1993)   2   (Shayesteh et al., 1999)  

All lines are ovarian carcinoma lines except for the breast cancer line MCF7.

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