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Keywords: vacuole
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Journal Articles
J Exp Biol (2000) 203 (1): 61–70.
Published: 1 January 2000
...Laurie A. Graham; Ben Powell; Tom H. Stevens ABSTRACT The proton-translocating ATPase (H + -ATPase) found on the membrane of the yeast vacuole is the best characterized member of the V-type ATPase family. Biochemical and genetic screens have led to the identification of 14 genes, the majority...
Journal Articles
J Exp Biol (2000) 203 (1): 71–80.
Published: 1 January 2000
...Michael Forgac ABSTRACT The vacuolar H + -ATPases (or V-ATPases) are a family of ATP-dependent proton pumps that carry out acidification of intracellular compartments in eukaryotic cells. This review is focused on our work on the V-ATPases of clathrin-coated vesicles and yeast vacuoles. The coated...
Journal Articles
Journal Articles
J Exp Biol (1994) 196 (1): 157–166.
Published: 1 November 1994
... into the vacuole and secretory organelles, respectively. The function of either Ca 2+ pump is sufficient for yeast viability, but deletion of both genes is lethal because of elevation of cytosolic [Ca 2+ ] and activation of calcineurin, a Ca 2+ -and calmodulin-dependent protein phosphatase. Calcineurin activation...
Journal Articles
J Exp Biol (1992) 172 (1): 105–112.
Published: 1 November 1992
...Morris F. Manolson; Denys Proteau; Elizabeth W. Jones ABSTRACT Vacuoles purified from Saccharomyces cerevisiae bearing the vphl-1 mutation had no detectable bafilomycin-sensitive ATPase activity or ATP-dependent proton pumping. Furthermore, the vacuolar H + -ATPase (V-ATPase) nucleotide binding...
Journal Articles
J Exp Biol (1992) 172 (1): 67–81.
Published: 1 November 1992
... available information on the VMA genes and the molecular biological functions of the VMA gene products. © 1992 by Company of Biologists 1992 V-ATPase VMA genes Saccharomyces cerevisiae vacuole The fungal vacuole is an acidic compartment which plays essential roles in metabolic...
Journal Articles
J Exp Biol (1992) 172 (1): 47–55.
Published: 1 November 1992
...Tom H. Stevens ABSTRACT The fungal vacuole is a prominent organelle that functions as a storage site for amino acids, Ca 2+ , storage carbohydrates, inorganic phosphate and numerous hydrolases ( Fig. 1 ) ( Klionsky et al . 1990 ). A hallmark of fungal vacuoles is that they are acidic compartments...