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Keywords: vaccine
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Journal Articles
J Exp Biol (2003) 206 (21): 3771–3779.
Published: 01 November 2003
...Susanna J. Dunachie; Adrian V. S. Hill SUMMARY Malaria is an intracellular pathogen, for which an effective vaccine is likely to require induction of cell-mediated immunity. Immunisation approaches that stimulate strong and persistent levels of effector T-cells are being sought by many researchers...
Journal Articles
J Exp Biol (2003) 206 (21): 3781–3788.
Published: 01 November 2003
...Siddhartha Mahanty; Allan Saul; Louis H. Miller SUMMARY The use of asexual blood-stage proteins as malaria vaccines is strongly supported by experimental data directly implicating antibodies induced by these antigens in parasite clearance and protection from re-challenge. The selection of blood...
Journal Articles
J Exp Biol (2003) 206 (21): 3789–3802.
Published: 01 November 2003
... effective immunity against the target pathogen is problematic, particularly if the genome is large. Malaria is an attractive model for the development and validation of approaches to translate genomic information to vaccine development because of the critical need for effective anti-malarial interventions...