... in a snail model of neuronal ageing. Through measuring the removal of 5(6)-carboxyfluorescein, a known substrate for membrane efflux transporters, we provide, for the first time, physiological evidence for the existence of probenecid-, MK571- and glutathione-sensitive efflux transporters in (gastropod...

... + /K + -ATPase inhibitor ouabain (10 mmol l –1 ; 21% reduction) and the vacuolar H + -ATPase inhibitor bafilomycin (5 μmol l –1 ; 21% reduction), and by the organic anions PAH (10 mmol l –1 ; 44% reduction) and probenecid (10 mmol l –1 ; 61% reduction, concentration-dependent inhibition). Transport...

... of Biologists 2000 organic anion transport Malpighian tubule Drosophila melanogaster probenecid colchicine. Larval and adult fruit flies, Drosophila melanogaster , feed on rotting fruit, which may contain large amounts of organic anions produced by microorganisms or excreted by other...

...′-monophosphates of guanosine (cGMP), inosine (cIMP) and uridine (cUMP). However, stimulation of the FSR by the 3′,5′ -monophosphate of cytidine (cCMP) was little affected by diodrast. Probenecid (0.2 or 1 mmol l −1 ) consistently stimulated the FSR, on average by approximately 25 %, but did not markedly inhibit...