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Keywords: presenilin
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Journal Articles
Vijaya B. Kumar, Mark Franko, William A. Banks, Pranav Kasinadhuni, Susan A. Farr, Kamlesh Vyas, Veena Choudhuri, John E. Morley
Journal:
Journal of Experimental Biology
J Exp Biol (2009) 212 (4): 494–498.
Published: 15 February 2009
... of presenilin-1 (PS1), nicastrin, APH-1 and Pen-2. As PS1 has been shown to play a critical role in facilitating γ-secretase activity,and mutations in this protein are associated with familial AD (FAD), we have cloned it from SAMP8 mouse hippocampus and compared its sequence with those of other species...
