... 2011. 2011 EPO phenylhydrazine anemia erythropoiesis Xenopus laevis colony assay Oxygen is required for sustaining the life of animals through the production of energy (Bunn and Poyton, 1996). In vertebrates, erythrocytes carry oxygen to tissues; therefore, the maintenance...

... of icefish, we chemically induced severe anemia in a red-blooded notothenioid, Notothenia coriiceps . After 10 days of treatment with phenylhydrazine HCl, the hematocrit and Hb concentration of N. coriiceps decreased by >90% and >70%, respectively. Anemic fish exhibited a significantly higher...