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Keywords: p-glycoprotein
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Journal Articles
Journal Articles
J Exp Biol (1998) 201 (1): 21–31.
Published: 1 January 1998
... of a 170 kDa membrane protein identified as P-glycoprotein and reversal of resistance by verapamil and quinine. Compared with NG108-15 cells, NG/DOXR cells showed an increase in Na + current density and a decrease in cyclic-AMP-activated Cl − current density with no change in K + - and volume-sensitive Cl...
Journal Articles
J Exp Biol (1994) 196 (1): 15–49.
Published: 1 November 1994
... characteristics, such as their coupling to electrochemical ion gradients or ATP hydrolysis. The findings that most transporters are composed of 6 or 12 membrane-spanning domains and that highly homologous ATP-binding domains are found in both bacterial periplasmic permeases and eukaryotic P-glycoproteins strongly...