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Keywords: oxidative damage
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Journal Articles
J Exp Biol (2021) 224 (18): jeb243116.
Published: 14 September 2021
...Michael W. Butler; Emma N. Stierhoff; Julianna M. Carpenetti; Matthew A. Bertone; Alyssa M. Addesso; Sarah A. Knutie ABSTRACT The purpose of mounting an immune response is to destroy pathogens, but this response comes at a physiological cost, including the generation of oxidative damage. However...
Journal Articles
J Exp Biol (2021) 224 (6): jeb233486.
Published: 26 March 2021
..., is accompanied by changes in oxidative status. We induced autumn migration followed by a non-migratory wintering phase in common quails ( Coturnix coturnix ). We compared three markers of oxidative status – oxidative damage to lipids expressed as thiobarbituric acid reactive substances (TBARS); superoxide...
Includes: Supplementary data
Journal Articles
J Exp Biol (2019) 222 (18): jeb204925.
Published: 23 September 2019
... damage in some tissues. Telomeres, which are the terminal sequences of linear chromosomes, may shorten in the presence of ROS, and thus the telomere length of an individual reflects the degree of accrued oxidative damage. This study quantified telomere length dynamics throughout hibernation in arctic...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (6): jeb171009.
Published: 23 March 2018
... oxygen species (ROS) are generated slowly and buffered by antioxidants ( Turrens, 2003 ), thereby minimizing oxidative damage. Activity rates that exceed oxygen delivery rate cause elevated ROS generation and damage to cellular components such as lipids ( Rubbo et al., 1994 ), proteins ( Stadtman...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (5): jeb162503.
Published: 01 March 2018
... proteins, and antioxidants were higher in red-blooded fishes than in Hb-less icefishes in some tissues, this pattern did not persist across all tissues. Expression of Mb was not associated with oxidative damage in the heart ventricle, whereas the activity of citrate synthase and the contents of heme were...
Includes: Supplementary data
Journal Articles
J Exp Biol (2017) 220 (10): 1792–1796.
Published: 15 May 2017
... ( Vipera aspis ), a species naturally exposed to periods of water and food deprivation. We predicted a cumulative effect of pregnancy and dehydration on oxidative stress levels. Our results support the occurrence of an oxidative cost of reproduction as we found higher oxidative damage levels in pregnant...
Includes: Supplementary data
Journal Articles
J Exp Biol (2015) 218 (24): 3901–3910.
Published: 01 December 2015
... success or survival, but the physiological mechanisms underlying these costs are still obscure. To test for a role of oxidative stress, we measured oxidative damage to lipids and proteins in liver, heart, kidneys and muscles, as well as the level of antioxidants (total glutathione and catalase...
Journal Articles
J Exp Biol (2015) 218 (13): 1981–1985.
Published: 01 July 2015
... predicted that males would experience greater oxidative stress than females and that oxidative stress would reflect sex-specific measures of reproductive effort. Males, relative to females, had higher concentrations of 8-OHdG and malondialdehyde, which are markers of DNA oxidative damage and lipid...
Includes: Supplementary data
Journal Articles
J Exp Biol (2014) 217 (23): 4237–4243.
Published: 01 December 2014
... in oxidative damage, an increase in ceruloplasmin (which is upregulated in response to oxidative damage) and a decrease in thiol antioxidants. We also compared the blood oxidative stress level of reproducing birds with that of non-reproducing birds, a crucial aspect that most studies have invariably failed...
Journal Articles
J Exp Biol (2014) 217 (19): 3407–3415.
Published: 01 October 2014
... framework for abiotic factors influencing DGE is proposed in which the following stressors are prioritized in decreasing order of importance: oxygen supply, CO 2 excretion and pH modulation, oxidative damage protection and water savings. * Author for correspondence ( berg@sun.ac.za ) Author...
Includes: Supplementary data
Journal Articles
J Exp Biol (2014) 217 (18): 3301–3310.
Published: 15 September 2014
...Laura A. Enzor; Sean P. Place Antarctic fish of the suborder Notothenioidei have evolved several unique adaptations to deal with subzero temperatures. However, these adaptations may come with physiological trade-offs, such as an increased susceptibility to oxidative damage. As such, the expected...
Includes: Supplementary data
Journal Articles
J Exp Biol (2014) 217 (9): 1478–1484.
Published: 01 May 2014
...Viviana Marri; Heinz Richner Oxidative stress is the imbalance between the production of reactive species and antioxidants, which causes damage to lipids, proteins and DNA. Antioxidants, like vitamins and carotenoids, can limit oxidative damage and can therefore regulate the trade-off between...
Journal Articles
J Exp Biol (2013) 216 (22): 4242–4250.
Published: 15 November 2013
... bactericidal capacity and size of the thymus) were significantly suppressed, while some measures of oxidative protection [serum superoxide dismutase (SOD) activity and glutathione peroxidase (GPx) activity] were also reduced, and a marker of oxidative damage (protein carbonyls in serum) was increased...
Includes: Supplementary data
Journal Articles
J Exp Biol (2013) 216 (14): 2713–2721.
Published: 15 July 2013
... of oxidative damage to DNA bases and assessment of erythrocyte glutathione levels. * Author for correspondence ( horak@ut.ee ) AUTHOR CONTRIBUTIONS P.H., R.M. and E.S. designed the study; R.M. and E.S. executed the experiment; R.M., E.S., K.K. and R.P. performed the analyses; and P.H. and R.M...
Journal Articles
J Exp Biol (2013) 216 (12): 2213–2220.
Published: 15 June 2013
... also dropped ( Jones, 2006 ; Sohal and Orr, 2012 ). Consequently, an increase in the production of free radicals might not have been tackled by the antioxidant response, leading to an increase in oxidative damage. It is also worth highlighting that oxidation of molecules involved in redox regulation...
Includes: Supplementary data
Journal Articles
J Exp Biol (2013) 216 (6): 1012–1024.
Published: 15 March 2013
... species (ROS) in disused muscles may lead to oxidative stress, which in turn is associated with increased atrophic or apoptotic signalling and/or oxidative damage to the muscle and thus muscle disuse atrophy. Increases in the rate of oxygen consumption likely increase the overall generation of ROS in vivo...
Journal Articles
J Exp Biol (2012) 215 (16): 2820–2826.
Published: 15 August 2012
.... , Shirakawa H. , Toyomizu M. ( 2010 ). Metabolic characteristics and oxidative damage to skeletal muscle in broiler chickens exposed to chronic heat stress . Comp. Biochem. Physiol. 155A , 401 - 406 . Bartling B. , Friedrich I. , Silber R. E. , Simm A. ( 2003...
Includes: Supplementary data
Journal Articles
J Exp Biol (2012) 215 (11): 1799–1805.
Published: 01 June 2012
.... We measured oxidative damage to lipids and proteins in breeding bank vole ( Myodes glareolus ) females after rearing one and two litters, and in non-breeding females. We used bank voles from lines selected for high maximum aerobic metabolic rates (which also had high resting metabolic rates and food...
Journal Articles
J Exp Biol (2011) 214 (7): 1148–1152.
Published: 01 April 2011
... on oxidative damage and circulating carotenoids in captive adult kestrels (Falco tinnunculus) . J. Comp. Physiol. B 178 , 829 - 835 . Csermely P. , Soti C. ( 2006 ). Cellular networks and the aging process . Arch. Physiol. Biochem. 112 , 60 - 64 . Dotan Y. , Lichtenberg...
Journal Articles
J Exp Biol (2010) 213 (13): 2225–2233.
Published: 01 July 2010
... ) 17 3 2010 © 2010. 2010 In the current study, we address the question about the links between oxidative damage, systemic GSH levels and melanin- and carotenoid-based feather coloration in captive greenfinches. Greenfinches are an excellent model for looking at the mechanisms affecting...
Includes: Supplementary data