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Keywords: obesity
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Journal Articles
Journal Articles
J Exp Biol (2021) 224 (2): jeb219543.
Published: 26 January 2021
...Daniella E. Chusyd; Tim R. Nagy; Lilian Golzarri-Arroyo; Stephanie L. Dickinson; John R. Speakman; Catherine Hambly; Maria S. Johnson; David B. Allison; Janine L. Brown ABSTRACT Many captive Asian elephant populations are not self-sustaining, possibly due in part to obesity-related health...
Includes: Supplementary data
Journal Articles
J Exp Biol (2020) 223 (14): jeb228379.
Published: 22 July 2020
... a reduction in glycogen stores yet increase flight activity without changing rates of glycogen depletion. Drosophila Energy Metabolism Obesity Plasticity Protein Glycogen is a critical store of energy for supplying the energetic demands of locomotion in many animals ( Hochachka, 1985...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Exp Biol (2018) 221 (Suppl_1): jeb167254.
Published: 7 March 2018
...John R. Speakman; Raul K. Suarez; Hans H. Hoppeler ABSTRACT Human obesity has a large genetic component, yet has many serious negative consequences. How this state of affairs has evolved has generated wide debate. The thrifty gene hypothesis was the first attempt to explain obesity as a consequence...
Journal Articles
J Exp Biol (2016) 219 (2): 259–265.
Published: 1 January 2016
...Lena Cron; Tamara Allen; Mark A. Febbraio; Stan L. Lindstedt; Hans H. Hoppeler ABSTRACT It is well known that obesity is responsible, at least in part, for the increased incidence of chronic diseases such as type 2 diabetes, cardiovascular disease and certain types of cancer. Despite public...
Journal Articles
J Exp Biol (2015) 218 (1): 50–58.
Published: 1 January 2015
... and disease’ (DOHaD) is at stake and therefore requires a paradigm shift. Maternal obesity and malnutrition predispose offspring to develop metabolic syndrome, a vicious cycle leading to transmission to subsequent generation(s), with differences in response and susceptibility according to the sex...
Journal Articles
Journal Articles
Journal Articles
J Exp Biol (2008) 211 (19): 3103–3110.
Published: 1 October 2008
.... Here we show that mutation of the Drosophila adipokinetic hormone receptor (AKHR), a functional analog of the mammalian glucagon receptor, leads to abnormal accumulation of both lipid and carbohydrate. As a consequence of their obese phenotypes, AKHR mutants are markedly starvation resistant. We show...
Journal Articles
J Exp Biol (2004) 207 (16): 2859–2866.
Published: 15 July 2004
... changes in energy balance. * Author for correspondence (e-mail: Klaus@mail.dife.de ) 1 6 2004 © The Company of Biologists Limited 2004 2004 body mass set-point energy expenditure body composition ponderostat obesity gravity sex difference mice The set-point theory...
Journal Articles
J Exp Biol (2002) 205 (15): 2275–2285.
Published: 1 August 2002
...) energy metabolism, which would be consistent with the observations from linkage and association studies. Therefore, UCP2 and UCP3 remain interesting targets for pharmacological upregulation in the treatment of obesity and diabetes. References Boss, O., Samec, S., Desplanches, D., Mayet, M.-H...
Journal Articles
J Exp Biol (2000) 203 (2): 295–300.
Published: 15 January 2000
...Peter H. Niewiarowski; Michelle L. Balk; Richard L. Londraville ABSTRACT Leptin is a hormone that regulates energy expenditure and body mass in mammals, and it has attracted considerable attention because of its potential in treating human obesity. Comprehensive data from both pathological and non...