...Danielle Mack; Andrew Yevugah; Kenneth Renner; Brian D. Burrell ABSTRACT Noxious stimuli can elicit stress in animals that produce a variety of adaptations including changes in responses to nociceptive and non-nociceptive sensory input. One example is stress-induced analgesia that may be mediated...

...Jack S. Thomson; Anthony G. Deakin; Andrew R. Cossins; Joseph W. Spencer; Iain S. Young; Lynne U. Sneddon ABSTRACT The state of an animal prior to the application of a noxious stimulus can have a profound effect on their nociceptive threshold and subsequent behaviour. In mammals, the presence...

..., but the identity of the nociceptive sensory neurons are currently unknown. It is also not known whether both mechanical and thermal stimuli are detected by the same neurons. Here, we show that the likelihood of a strike increases with the strength of the stimulus and that activity in nerves innervating the body...

...Javier Lopez-Luna; Qussay Al-Jubouri; Waleed Al-Nuaimy; Lynne U. Sneddon ABSTRACT Research has recently demonstrated that larval zebrafish show similar molecular responses to nociception to those of adults. Our study explored whether unprotected larval zebrafish exhibited altered behaviour after...

... be thermodetectors in many animal phyla. In this study, we provide the first pharmacological evidence of a putative TRPA1-like channel in the medicinal leech. The leech's polymodal nociceptive neuron was activated by both peripheral and central application of the TRPA1 agonist AITC in a concentration-dependent...

... the presence of a putative TRPV-like receptor in the medicinal leech, building upon earlier studies in this lophotrochozoan invertebrate. The leech polymodal nociceptive neuron was activated by both peripheral and central application of the TRPV1-activator capsaicin in a concentration-dependent manner...

...Barry Magee; Robert W. Elwood SUMMARY Nociception allows for immediate reflex withdrawal whereas pain allows for longer-term protection via rapid learning. We examine here whether shore crabs placed within a brightly lit chamber learn to avoid one of two dark shelters when that shelter consistently...

... the two different afferent types. To determine whether the receptors have a nociceptive function, a range of chemical stimulants was applied to these receptors, including non-noxious stimuli such as ammonium chloride, bile, sodium bicarbonate and alarm pheromone, and potentially noxious chemical irritants...

... of Bristol, Bristol BS8 1TD, UK † Author for correspondence ( s.r.soffe@bristol.ac.uk ) 6 7 2011 © 2011. 2011 epithelial impulse nociception growth cone REFERENCES Alpert M. H. , Zhang H. Y. , Molinari M. , Heitler W. J. , Sillar K. T. ( 2007...

... to the distal third of one arm, we show that a cephalopod expresses behavioral alterations persisting for at least 2 days after injury. These alterations parallel forms of nociceptive plasticity in other animals, including general and site-specific sensitization to tactile stimuli. A novel finding is that hyper...