... Nicotinic acetylcholine receptor Thiamethoxam Apis mellifera Odour discrimination Cholinergic signalling Since the beginning of the 20th century, agriculture has increasingly relied on industrial chemicals that kill or repel insect pests, fungi, non-crop plants and plant pathogens. Thousands...

... contractions and the basal tone of mammalian smooth muscle, a response not blocked by treatment with TTX, providing additional evidence for a postsynaptic site of action ( Minocha and Galligan, 1993 ). GABA A antagonists can also bind to nicotinic acetylcholine receptors (nAChRs) because of a structural...

... sensitivities to 0.1 μmol l −1 α-bungarotoxin (α-BTX), which selectively blocks AChRs with ‘mixed’ nicotinic/muscarinic pharmacology in this preparation. This indicates that Imidacloprid affects both AChRs sensitive to α-BTX and α-BTX-insensitive nicotinic acetylcholine receptors (nAChRs). Thus...

...Camilla Tornøe; Lindy Holden-Dye; Catherine Garland; Stewart N. Abramson; John T. Fleming; David B. Sattelle ABSTRACT Nematode nicotinic acetylcholine receptors (nAChRs) are molecular targets of several anthelmintic drugs. Studies to date on Caenorhabditis elegans and Ascaris suum have demonstrated...

...S. D. Buckingham; S. C. R. Lummis; M. L. Balk; M. Schroeder; D. B. Sattelle ABSTRACT Electrophysiology and binding studies were used to determine the actions of vesamicol [2-(4-phenylpiperidino)cyclohexanol, (AH5183)] on an α-bungarotoxin-sensitive, neuronal nicotinic acetylcholine receptor...

...C. A. Leech; D. Bai; D. B. Sattelle 30 4 1992 © 1992 by Company of Biologists 1992 dithiothreitol nicotinic acetylcholine receptor neurone cockroach Periplaneta americana disulphide bond Nicotinic acetycholine receptors are present at high density in the nervous...

... 63104, USA. † Present address: Laboratoire de Physiologie, Faculté de Médecine, UA CNRS No 611, Université d’Angers, Angers 49045, France. 4 7 1988 © 1989 by Company of Biologists 1989 κ -Bungarotoxin (= kappa-Bungarotoxin) nicotinic acetylcholine receptor excitatory...