...@csuhayward.edu ) 7 12 2004 © The Company of Biologists Limited 2005 2005 cell calcium amphibian Rana catesbeiana neuroprotection anoxia Fura 2-FF BTC Fura-AM propidium iodide Mammalian neurons are typically intolerant of anoxic conditions, and short periods of anoxia...

... a significant role in the nervous system. Both EPO and its receptor are expressed throughout the brain in glial cells, neurones and endothelial cells. Hypoxia and ischaemia have been recognised as important driving forces of EPO expression in the brain. EPO has potent neuroprotective properties in vivo...