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Keywords: neuropeptide
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Journal Articles
J Exp Biol (2020) 223 (2): jeb207407.
Published: 29 January 2020
... identified several head-expressed genes strongly responding to social isolation or enrichment. Of particular interest, social isolation downregulated expression of the gene encoding the neuropeptide Drosulfakinin (Dsk), the homologue of vertebrate cholecystokinin (CCK), which is critical for many mammalian...
Includes: Supplementary data
Journal Articles
J Exp Biol (2019) 222 (21): jeb207985.
Published: 06 November 2019
.../ Summary: C-type allatostatin and its receptor are involved in the regulation of ovarian development in Scylla paramamosain , possibly by directly inhibiting the uptake of yolk by oocytes and obstructing oocyte growth. Neuropeptide Vitellogenesis Endocrine The allatostatins (ASTs) are the...
Journal Articles
J Exp Biol (2019) 222 (13): jeb201319.
Published: 05 July 2019
... encoded by two distinct genes with a similar organization were also characterized. These oyster neuropeptides (Cragi-CT1/2) exhibit the two N-terminal paired cysteine residues and, except CTP2-derived peptide (Cragi-CTP2dp), show the C-terminal proline-amide motif typical of deuterostome CT-type peptides...
Includes: Supplementary data
Journal Articles
J Exp Biol (2019) 222 (2): jeb194092.
Published: 18 January 2019
... the lobster nervous system, we hypothesized that they might function as neuromodulators, as is common for neuropeptides. We thus asked whether AMGSEFLamide modulates the rhythmic outputs of the cardiac ganglion and the stomatogastric ganglion. Physiological recordings showed that AMGSEFLamide potently...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (3): jeb151092.
Published: 09 February 2018
...Maurice R. Elphick; Olivier Mirabeau; Dan Larhammar ABSTRACT Neuropeptides are a diverse class of neuronal signalling molecules that regulate physiological processes and behaviour in animals. However, determining the relationships and evolutionary origins of the heterogeneous assemblage of...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (3): jeb166710.
Published: 08 February 2018
...Gáspár Jékely; Sarah Melzer; Isabel Beets; Ilona C. Grunwald Kadow; Joris Koene; Sara Haddad; Lindy Holden-Dye ABSTRACT Neuropeptides are the most diverse class of chemical modulators in nervous systems. They contribute to extensive modulation of circuit activity and have profound influences on...
Journal Articles
J Exp Biol (2017) 220 (18): 3381–3390.
Published: 15 September 2017
... feeding pauses. Antibodies against these neuropeptides label cells that express the neurosecretory proteins and voltage-gated calcium channels implicated in regulated secretion. These cells are embedded in the ventral epithelium, where they comprise only 4% of the total, and are concentrated around the...
Includes: Supplementary data
Journal Articles
J Exp Biol (2016) 219 (15): 2388–2395.
Published: 01 August 2016
... holometabolous (Endopterygota) insects within the order Diptera. We show that crustacean cardioactive peptide (CCAP), FMRFamide and SALDKNFMRFamide increase the contraction rate of the antennal APOs and the heart of Anopheles gambiae . Both antennal hearts are synchronously responsive to these neuropeptides, but...
Journal Articles
J Exp Biol (2016) 219 (9): 1327–1336.
Published: 01 May 2016
... expression of hypothalamus neuropeptide Y (NPY) and the anorexigenic neuropeptides pro-opiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART) did not differ among females raising small, medium and large litters. Leptin levels in lactation may only reflect a state of energy balance...
Journal Articles
J Exp Biol (2015) 218 (18): 2892–2904.
Published: 01 September 2015
... modulates cardiac activity, suggesting high isoform specificity of the pyrokinin receptor(s) in this tissue. Central pattern generator Neuromodulation Neuropeptide The central pattern generator (CPG)-effector systems of invertebrates have previously and continue to provide valuable...
Journal Articles
J Exp Biol (2015) 218 (4): 551–561.
Published: 15 February 2015
...Stefan Gründer; Marc Assmann; Peter A. V. Anderson Neurons either use electrical or chemical synapses to communicate with each other. Transmitters at chemical synapses are either small molecules or neuropeptides. After binding to their receptors, transmitters elicit postsynaptic potentials, which...
Includes: Supplementary data
Journal Articles
J Exp Biol (2014) 217 (10): 1725–1736.
Published: 15 May 2014
...Maja Milakovic; Kiel G. Ormerod; Markus K. Klose; A. Joffre Mercier Drosophila melanogaster is a model system for examining the mechanisms of action of neuropeptides. DPKQDFMRFamide was previously shown to induce contractions in Drosophila body wall muscle fibres in a Ca 2+ -dependent manner. The...
Journal Articles
J Exp Biol (2013) 216 (4): 601–613.
Published: 15 February 2013
... structure in the malaria mosquito Anopheles gambiae , assessed the developmental expression of CCAP and its receptor and determined the role that CCAP plays in regulating mosquito cardiac function. RACE sequencing revealed that the A. gambiae CCAP gene encodes a neuropeptide that shares 100% amino acid...
Includes: Multimedia, Supplementary data
Journal Articles
J Exp Biol (2012) 215 (21): 3758–3767.
Published: 01 November 2012
... take a blood meal to produce a second egg clutch. Decapitation of females shortly after emergence or blood ingestion prevents egg maturation. Here, we report that a single injected dose of the neuropeptide ovary ecdysteroidogenic hormone (OEH) fully restored egg maturation in decapitated females in...
Journal Articles
J Exp Biol (2012) 215 (13): 2308–2318.
Published: 01 July 2012
... 20001, USA 9 1 2012 12 3 2012 © 2012. 2012 allatostatin crustacean modulation neuropeptide While it is well established that modulatory inputs, both neuronal and hormonal, can alter the outputs of central pattern generators (CPGs) to modulate rhythmic patterns of...
Journal Articles
J Exp Biol (2011) 214 (13): 2242–2247.
Published: 01 July 2011
... the leptin receptor (Ob-Rb), suppressor-of-cytokine-signalling-3 (SOCS-3), neuropeptide Y (NPY), agouti-related protein (AgRP), pro-opiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART) in the hypothalamus were examined on dioestrous, day 5, day 17 of lactation and day 27 (1...
Journal Articles
J Exp Biol (2010) 213 (1): 118–127.
Published: 01 January 2010
..., the first demonstration of CLDH bioactivity outside the Insecta, and the first detection of an intrinsic neuropeptide transcript in the crustacean CG. * Author for correspondence ( achristi@mdibl.org ) 21 9 2009 © 2010. 2010 calcitonin-like diuretic hormone (CLDH) cardiac...
Journal Articles
J Exp Biol (2009) 212 (24): 3961–3976.
Published: 15 December 2009
...J. S. Stevens; C. R. Cashman; C. M. Smith; K. M. Beale; D. W. Towle; A. E. Christie; P. S. Dickinson SUMMARY pQDLDHVFLRFamide is a highly conserved crustacean neuropeptide with a structure that places it within the myosuppressin subfamily of the FMRFamide-like peptides. Despite its apparent...
Journal Articles
J Exp Biol (2009) 212 (19): 3142–3147.
Published: 01 October 2009
... for a diuretic hormone, DH 44 . Here, we report that the other CRF receptor subfamily member, encoded by CG12370 , is also a receptor for the DH 44 neuropeptide. The lines of evidence to support this identification include increases in cAMP levels due to CG12370 receptor activation and the recruitment...
Journal Articles
J Exp Biol (2009) 212 (8): 1067–1077.
Published: 15 April 2009
...Maurice R. Elphick; Matthew L. Rowe SUMMARY The myoactive neuropeptide NGIWYamide was originally isolated from the holothurian (sea cucumber) Apostichopus japonicus but there is evidence that NGIWYamide-like peptides also occur in other echinoderms. Here we report the discovery of a gene in the sea...