... are classified on the basis of their myosin heavy chain (MHC) isoform composition, which are broadly categorised into slow and fast fibres. In humans, these are slow type I and IIa fibres, which are poised towards oxidative metabolism with high fatigue resistance, but low shortening velocity, force and power...

... fibres from four marmoset and nine human VL biopsies, the force–velocity characteristics were determined. Marmoset VL contained almost exclusively fast muscle fibres (>99.0%), of which 63% were type IIB and 37% were hybrid fibres, fibres containing multiple myosin heavy chains. GM contained 9% type I...

...Timothy F. Tirrell; Mark S. Cook; J. Austin Carr; Evie Lin; Samuel R. Ward; Richard L. Lieber SUMMARY The molecular components largely responsible for muscle attributes such as passive tension development (titin and collagen), active tension development (myosin heavy chain, MHC...

..., this period is usually marked by a fast maturation of muscles, during which different myosin heavy chain (MyHC) isoforms are expressed. However, parental food provisioning may fluctuate seasonally, and offspring therefore face a challenge to ensure the necessary maturation of their tissues when energy...

.... The results indicate that masticatory myosin is expressed in some Sciuridae species but not in other closely related species with similar diets but having different nut-opening strategies. We also discovered that the myosin light chain 1 isoform associated with masticatory myosin heavy chain, in the same four...

... with respect to endurance-running capacity. Plantar flexors in the mini-muscle phenotype exhibit a high capacity for aerobic activity, including altered enzyme activities, loss of expression of type II b myosin heavy chain (MHC), increased expression of type I,II x and II a MHC, and mechanical performance...

...Takami Morita SUMMARY The evolutionary adaptations of functional genes to life at high pressure are not well understood. To elucidate the mechanisms of protein adaptation to high pressure, we cloned the myosin heavy chain (MyHC) cDNA from skeletal muscle of two deep-sea fishes, Coryphaenoides...

... the hypothesis that changes in muscle protein composition underlie the observed changes in contractile performance. We found that gregarine infection was associated with a 10-fold average reduction in abundance of a ∼155 kDa fragment of muscle myosin heavy chain (MHC;∼206 kDa intact size). Insect MHC gene...

..., Pittsburgh, PA 15260, USA 5 6 2006 © The Company of Biologists Limited 2006 2006 spaceflight muscle remodeling Caenorhabditis elegans myosin heavy chain development The neuromuscular system is recognized as one of the physiologic systems most affected by spaceflight ( Fitts...

...Trina F. Galloway; Tora Bardal; Sylvia N. Kvam; Stine W. Dahle; Gaute Nesse; Markus Randøl; Elin Kjørsvik; Øivind Andersen SUMMARY Genes encoding the myogenic regulating factors MyoD and myogenin and the structural muscle proteins myosin light chain 2 (MyLC2) and myosin heavy chain(MyHC) were...

...Yoshiaki Nihei; Atsushi Kobiyama; Daisuke Ikeda; Yosuke Ono; Satoshi Ohara; Nicholas J. Cole; Ian A. Johnston; Shugo Watabe SUMMARY Three embryonic class II myosin heavy chains (MYHs) were cloned from the common carp ( Cyprinus carpio L.), MYH emb1 ,MYH emb2 and MYH emb3 . MYH DNA clones were also...

...Scott Medler; Travis Lilley; Donald L. Mykles SUMMARY In recent years, an increasing number of studies has reported the existence of single fibers expressing more than one myosin heavy chain (MHC) isoform at the level of fiber proteins and/or mRNA. These mixed phenotype fibers, often termed hybrid...

...Luana Toniolo; Marco Patruno; Lisa Maccatrozzo; Maria A. Pellegrino; Monica Canepari; Rosetta Rossi; Giuseppe D'Antona; Roberto Bottinelli; Carlo Reggiani; Francesco Mascarello SUMMARY Little is known about the influence of Myosin Heavy Chain (MHC) isoforms on the contractile properties of single...

... of the American lobster Homarus americanus . SDS-PAGE and western blotting were used to identify isoform assemblages of myosin heavy chain (MHC), P75, troponin T(TnT) and troponin I (TnI). RT-PCR was used to monitor expression of fast and slow (S 1 ) MHC, P75 and actin in different fiber types, and the MHC...

...Dario I. Carrasco; Arthur W. English SUMMARY During normal postnatal development, rat soleus (SOL) muscle fibers undergo a dramatic fast-to-slow myosin heavy chain (MyHC) isoform transformation. We exploited this phenomenon to evaluate the role of neurotrophin 4/5 (NT-4/5) in the regulation...

... © The Company of Biologists Limited 2002 2002 Etruscan shrew Suncus etruscus skeletal muscle extensor digitorum longus soleus fibre composition myosin heavy chain myosin light chain lactate dehydrogenase citrate synthase creatine kinase myoglobin Ca 2+ transient contraction...

.... To investigate the embryological development of fast and slow muscle in trout embryos, we carried out single and double in situ hybridisation with fast and slow myosin heavy chain (MyHC)-isoform-specific riboprobes. This showed that the slow-MyHC-positive cells originate in a region of the somite close...

...Margaret M. Briggs; Fred Schachat ABSTRACT Extraocular muscle (EOM) exhibits high-velocity, low-tension contractions compared with other vertebrate striated muscles. These distinctive properties have been associated with a novel myosin heavy chain (MyHC) isoform, MyHC-EO. An atypical MyHC, MyHC IIL...

... etruscus Crocidura russula skeletal muscle extensor digitorum longus soleus myosin heavy chain myosin light chain lactate dehydrogenase citrate synthase creatine kinase myoglobin parvalbumin Ca 2+ transient time to peak of force relaxation myosin ATPase fibre composition...

...Steven Ennion; David Wilkes; Laurent Gauvry; Hélene Alami-Durante; Geoffrey Goldspink ABSTRACT Whilst developmentally regulated genes for the myosin heavy chain ( MyoHC ) have been characterised in mammalian, avian and amphibian species, no developmental MyoHC gene has previously been characterised...