... and expression of stress proteins (heat shock proteins HSP60, HSP70 and HSP90) and metallothioneins in isolated gill and hepatopancreas cells of the eastern oyster, Crassostrea virginica . Our study showed that exposure to cadmium resulted in a dose-dependent increase in the rate of protein synthesis in oyster...

... by this species. One full-length clone of 1196 nucleotides (GenBank accession number AY034179) hybridized with a 1200-nucleotide band on northern blots and encoded a 100-amino-acid protein that was identified as belonging to the metallothionein (MT) family. L. littorea MT shared 45% and 56% identity...

...E. David Thompson; Gregory D. Mayer; Patrick J. Walsh; Christer Hogstrand SUMMARY Female squirrelfish (Holocentridae) accumulate higher concentrations of hepatic zinc than any other known organism. In the liver cells, up to 70% of zinc is bound to metallothionein (MT), which is expressed...

... be the primary benefit of zinc and copper storage. * e-mail: rmss@conch.uoregon.edu 23 09 1997 © 1997 The Company of Biologists Ltd. 1997 detoxification metallothionein PIXE STIM heavy metals toxins metabolism Drosophila melanogaster Drosophila hydei Heavy...

... high levels of two major zinc-binding proteins: metallothionein (MT) and a novel female-specific zinc-binding protein (FZnBP). In females, but not in males, almost all MT is present in the hepatocyte nucleus. FZnBP is exclusively found in the hepatocyte cytosol of females. Second, hepatocytes of female...

... of adaptation to Zn 2+ and increased metabolic cost. Depressed plasma [Ca] was corrected within 1 week, and there were no effects on whole-body [Ca] or [Zn]. A slight accumulation of Zn in the gills was associated with increased branchial metallothionein levels. Rates of protein synthesis and degradation...

... on both days 27 and 50). Unidirectional Zn 2+ influx, measured at the end of the exposure period, was significantly reduced in the Zn 2+ -exposed fish. There were no changes in hepatic or branchial Zn 2+ , Cu 2+ or metallothionein concentrations. We hypothesize that, during exposure to sublethal [Zn 2...