... homologous to the Smf1 protein from Saccharomyces cerevisiae , which we have recently demonstrated to function as a Mn 2+ /Zn 2+ transporter. We proposed that the Drosophila and mammalian proteins, like the yeast SMF1 gene product, are metal-ion transporters. To test this hypothesis, malvolio mutant flies...

... other metal-ion transporters. * Present address: Department of Molecular and Cellular Biology, University of California – Berkeley, Berkeley, CA 94720, USA. † Present address: Gladstone Institute of Cardiovascular Disease, University of California – San Francisco, San Francisco, CA 94141...