... 2020 29 3 2021 © 2021. Published by The Company of Biologists Ltd 2021 Summary: Cellular metabolic rate in primary fibroblast cells from dogs does not change with LPS treatment. However, IL-6 concentration increases with LPS treatment. Body mass Inflammaging Lifespan...

... and fitness is less clear. Here, we show that Drosophila exposed to hypoxia during their larval period subsequently show reduced starvation stress resistance and shorter lifespan as adults, with these effects being stronger in males. We find that these effects are associated with reduced whole-body insulin...

...Michael Poeschla; Dario R. Valenzano; Michael H. Dickinson; Leslie B. Vosshall; Julian A. T. Dow ABSTRACT Lifespan is a remarkably diverse trait in nature, ranging from just hours in adult mayflies to hundreds of years in the Greenland shark and quahog clam. Great disparities in lifespan are often...

..., which generally include a reduction in fitness of the carrier of the driving allele, making such systems ‘selfish’. The t haplotype is one such driver, found in house mice. It is linked to a reduction in litter size in matings among heterozygous animals, but also to increased lifespan in wild females...

..., with the nutritional optima being identified at P:C 1:4 for lifespan (P+C 120 g l −1 ), 1:2 for egg-to-adult viability (120 g l −1 ), 1:1 for female body mass at adult eclosion (240 g l −1 ) and lifetime fecundity (360 g l −1 ), 2:1 for larval developmental rate (60 g l −1 ) and 8:1 for egg production rate (120 g l −1...

...Oscar Vedder; Simon Verhulst; Erica Zuidersma; Sandra Bouwhuis ABSTRACT High growth rate is associated with a short lifespan, but the physiological basis for this trade-off is not well known. Telomere length predicts individual lifespan and in this study we investigated whether embryonic growth...

...Joseph W. Margotta; Stephen P. Roberts; Michelle M. Elekonich ABSTRACT Frequent and highly aerobic behaviors likely contribute to naturally occurring stress, accelerate senescence and limit lifespan. To understand how the physiological and cellular mechanisms that determine the onset and duration...

... time, reproduction and lifespan of the organism. Studies so far have focused on discriminating between protein and carbohydrate uptake and the consequences on fitness components at different life stages. However, it is largely unknown whether and how the developmental diets, which may entail habitat...

.... WJL even leads to a lifespan extension in nutritionally challenged males. These results demonstrate that L.p. WJL is a beneficial partner for Drosophila melanogaster through its entire life cycle. Thus, commensal bacteria allow the earlier emergence and longer survival of fit and fertile individuals...

..., where F1 foragers (median lifespan, 289 days; maximum lifespan, 409 days) lived as long as I1 inner-nest workers (median lifespan, 295 days; max. lifespan, 436 days; HR=1.18, P =0.126, Fig. 2 A). When F1 foragers were fed the most diluted high-carbohydrate food (median lifespan, 205 days; max...

... stress and defense responses to exogenous stressors. In order to rigorously examine correlations between pre-adult development time and other life history traits, we assayed pre-adult survivorship, starvation and desiccation resistance, body size and body weight, fecundity and adult lifespan in faster...

... invertebrate lifespan and induce aging-related physiological changes. However, the nature of the relationship between atmospheric oxygen, oxidative stress, and lifespan across a range of oxygen levels is poorly known. Developmental responses are likely to play a strong role, as prior research has shown strong...

... Lepidoptera lifespan Artificial flowers made from discs of coloured paper were used as stimuli (Daiei Training colour 200, Tokyo, Japan). The flower diameters were relative to the species' body size and were 5 cm for I. leuconoe and A. hyperbius , 4 cm for P. rapae and 3 cm for L. phlaeas...

...Hagai Rottenberg SUMMARY In animals, longevity (maximal lifespan) is inversely related to mass-specific basal metabolic rates. However, contrary to expectation, in several mammalian taxa, exceptional longevity is associated with high basal metabolic rate, and also fast evolution of mtDNA-coded...

... of membrane proteins. These differences in membrane composition may also represent a link between metabolism and aging. They probably explain the lifespan-body size relationship in mammals and birds and also the mammal-bird difference in lifespan. Most of the metabolic activity associated with basal...

...Yanmei Zhao; Hui Sun; Jun Lu; Xiaoxue Li; Xia Chen; Dan Tao; Weifeng Huang; Baiqu Huang SUMMARY The heat shock proteins (Hsps) play a positive role in lifespan determination, and histone acetylation has been shown to be involved in transcription of hsp genes in Drosophila . To further determine...