... ). Surviving hypoxia by modulation of mRNA translation rate . J. Cell. Mol. Med.   13   9A , 2770 - 2779 . Ge   P. , Luo   Y. , Liu   C. L. , Hu   B. ( 2007 ). Protein aggregation and proteasome dysfunction after brain ischemia . Stroke   38 , 3230 - 3236 . Guerriero   C. J...

... obligatory oxygen-dependent tissues, exposing seals to critical levels of ischemia and hypoxemia. The subsequent reperfusion/reoxygenation has the potential to increase oxidant production and thus oxidative stress. The contributions of extended apnea to oxidative stress in adapted mammals are not well...

... during ischemia, a technique that disrupts the available sensory feedback. Mechanical condition had a significant effect on both the preferred and resonant frequencies. Changes in preferred frequency scaled with resonant frequency, but the preferred frequency was significantly lower than the resonant...

... ischemia reperfusion maturation seal While diving, seals experience bradycardia and peripheral vasoconstriction to maximize the use of their oxygen stores and are consequently exposed to prolonged ischemia and hypoxemia ( Elsner, 1999 ; Kooyman and Ponganis, 1998 ; Meir et al., 2009...

... temperature ischemia reperfusion damage insect CO 2 production The deleterious effects of anoxia in humans (e.g. caused by ischemia) followed by reperfusion with O 2 , are well known and are a key topic in biomedical studies. As a model organism Drosophila melanogaster has the advantage of ease...

... be the physiological role(s) of neuroglobin in vertebrates. Nevertheless, there is no doubt that neuroglobin has an essential, conserved function and is beneficial to neurons. * Author for correspondence (e-mail: thorsten.burmester@uni-hamburg.de ) 3 3 2009 2009 globin mitochondria ischemia...

.... * Author for correspondence (e-mail: g.e.nilsson@bio.uio.no ) 12 3 2004 © The Company of Biologists Limited 2004 2004 anoxia hypoxia ischemia Carassius Hemiscyllium coral reef GABA glutamate Among vertebrates, those breathing water show the highest biodiversity...

... mechanisms of the thermostat, as well as the means that hibernating species use to tolerate such low body temperatures, may lead to therapeutic strategies when oxygen delivery is limited. Stimulation of the cerebellar fastigial nucleus protects against cerebral ischemia in rats( Reis et al., 1997...

... transient episodes of ischemia the decrease in oxygen supply or the oxidative damage caused by free radicals generated during reoxygenation may prove particularly fatal. Indeed, cumulative oxidative damage due to the toxic gain-of-function of mutant SOD1 has been linked to the pathogenesis of amyotrophic...

... parallels myocardial ischemia in vivo , where ischemic tissue becomes rapidly hypoxic and acidotic. Cardiac myocytes are resistant to chronic hypoxia at neutral pH but undergo extensive death when the extracellular pH (pH[o]) drops below 6.5. A microarray analysis of 20 000 genes (cDNAs and expressed...

...David S. Warner; Huaxin Sheng; Ines Batinić-Haberle SUMMARY Despite numerous defenses, the brain is vulnerable to oxidative stress resulting from ischemia/reperfusion. Excitotoxic stimulation of superoxide and nitric oxide production leads to formation of highly reactive products,including...

...Philip E. Bickler SUMMARY An effective treatment for brain ischemia is a pressing medical need. Research on brain ischemia has largely focused on understanding the mechanisms of neuron death as a way of identifying targets for therapy. An attractive alternative approach is to identify the survival...

... and ischemia experienced during a hibernation bout. * Author for correspondence (e-mail: kenneth_storey@carleton.ca ) 13 3 2002 © The Company of Biologists Limited 2002 2002 Spermophilus tridecemlineatus hibernation ischemia kidney cDNA library Many small mammals living...