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Keywords: insulin signaling
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Journal Articles

Central metabolic sensing remotely controls nutrient-sensitive endocrine response in Drosophila via Sir2/Sirt1–upd2–IIS axis

Kushal K. Banerjee, Rujuta S. Deshpande, Pranavi Koppula, Champakali Ayyub, Ullas Kolthur-Seetharam
Journal: Journal of Experimental Biology
J Exp Biol (2017) 220 (7): 1187–1191.
https://doi.org/10.1242/jeb.150805
Published: 1 April 2017
... linking obesity to insulin resistance and type 2 diabetes . Nat. Rev. Mol. Cell Biol.   9 , 367 - 377 . 10.1038/nrm2391 Hwangbo , D. S. , Gersham , B. , Tu , M.-P. , Palmer , M. and Tatar , M. ( 2004 ). Drosophila dFOXO controls lifespan and regulates insulin signalling...
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Journal Articles

Regulation of insulin-producing cells in the adult Drosophila brain via the tachykinin peptide receptor DTKR

Ryan T. Birse, Jeannette A. E. Söderberg, Jiangnan Luo, Åsa M. E. Winther, Dick R. Nässel
Journal: Journal of Experimental Biology
J Exp Biol (2011) 214 (24): 4201–4208.
https://doi.org/10.1242/jeb.062091
Published: 15 December 2011
... of intense studies of insulin signaling in Drosophilag the regulation of DILP production and release in adult fruit flies is poorly understood. Here we investigated the role of Drosophila tachykinin-related peptides (DTKs) and their receptors, DTKR and NKD, in the regulation of brain insulin-producing cells...
View article titled, Regulation of insulin-producing cells in the adult Drosophila brain via the tachykinin peptide receptor DTKR
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Includes: Supplementary data
Journal Articles

Gliclazide increases insulin receptor tyrosine phosphorylation but not p38 phosphorylation in insulin-resistant skeletal muscle cells

Naresh Kumar, Chinmoy S. Dey
Journal: Journal of Experimental Biology
J Exp Biol (2002) 205 (23): 3739–3746.
https://doi.org/10.1242/jeb.205.23.3739
Published: 1 December 2002
... of the present study was to test the hypothesis that gliclazide, a second-generation sulfonylurea, could enhance insulin signaling in insulin-resistant skeletal muscle cells. We demonstrated that gliclazide enhanced insulin-stimulated insulin receptor tyrosine phosphorylation in insulin-resistant skeletal muscle...
View article titled, Gliclazide increases insulin receptor tyrosine phosphorylation but not p38 phosphorylation in insulin-resistant skeletal muscle cells
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